Department of Pathophysiology, Medical University of Silesia, Katowice, Poland.
Obes Facts. 2008;1(5):274-9. doi: 10.1159/000169831. Epub 2008 Oct 23.
Dairy products not only reduce the risk of hypertension and cardiovascular diseases but may play a role in the treatment of obesity. As there is some evidence that calcium (Ca) and vitamin D may play a role in effective weight management, we decided to evaluate the influence of Ca and vitamin D supplementation on weight and fat loss in obese women.
Forty obese women were enrolled in this study. Subjects were divided into 2 groups comparable with body mass index (BMI) and age. Group 1 was provided with calcium carbonate and 1-(OH)-vitamin D supplementation. Group 2 was provided with only a diet. Subjects participated in a 3-month weight reduction therapy (balanced diet, modification of life style, and regular physical exercise). Blood samples (serum concentration of Ca, phosphorus (P), parathormone (PTH), 25-(OH)-D3) and clinical characteristics (weight, height, BMI, body composition) were taken at baseline and after the 3-month program.
No significant differences of body weight, body fat content, serum parathormone, 25-(OH)-D3 concentration, and plasma total Ca and P concentration were observed between analyzed groups both before and after the treatment. Additionally, we did not observe any significant influence of Ca and vitamin D supplementation on weight and fat loss.
Ca plus vitamin D supplementation during a 3-month low caloric diet has no additional effect on weight and fat loss in obese women.
乳制品不仅能降低高血压和心血管疾病的风险,还可能在肥胖治疗中发挥作用。由于有证据表明钙(Ca)和维生素 D 可能在有效的体重管理中发挥作用,我们决定评估 Ca 和维生素 D 补充对肥胖女性体重和体脂减少的影响。
这项研究纳入了 40 名肥胖女性。受试者按体重指数(BMI)和年龄分为两组。第 1 组给予碳酸钙和 1-(OH)-维生素 D 补充剂。第 2 组仅给予饮食。受试者参加了为期 3 个月的减肥治疗(均衡饮食、生活方式改变和定期体育锻炼)。在基线和 3 个月方案后采集血样(血清 Ca、磷(P)、甲状旁腺激素(PTH)、25-(OH)-D3 浓度)和临床特征(体重、身高、BMI、身体成分)。
在治疗前后,分析组之间的体重、体脂含量、血清甲状旁腺激素、25-(OH)-D3 浓度以及血浆总 Ca 和 P 浓度均无显著差异。此外,我们没有观察到 Ca 和维生素 D 补充对体重和体脂减少有任何显著影响。
在低热量饮食的 3 个月期间补充 Ca 加维生素 D 对肥胖女性的体重和体脂减少没有额外作用。