Ivanova A E, Aslanidi K B, Karpenko Iu V, Belozerskaia T A
Mikrobiologiia. 2005 Nov-Dec;74(6):756-65.
The effect of hydrogen peroxide ( 10(-9)-10(-1) M) on the mycelial growth of the fungi Alternaria alternata, Cladosporium cladosporioides, Mucor hiemalis, and Paecilomyces lilacinus has been studied. The growth of fungi isolated from habitats with a background level of radioactive contamination was stopped by H2O2 concentrations equal to 10(-3) and 10(-2) M, whereas the growth of fungi that were isolated from habitats with high levels of radioactive contamination was only arrested by 10(-1) M H2O2. The response of the different fungi to hydrogen peroxide was of three types: (1) a constant growth rate of fungal hyphae at H2O2 concentrations between 10(-9) and 10(-4) M and a decrease in this rate at 10(-3) M H2O2, (2) a gradual decrease in the growth rate as the H2O2 concentration was increased, and (3) an increase in the growth rate as the H2O2 concentration was increased from 10(-7) to 10(2)-5 M. The melanin-containing species A. alternata and C. cladosporioides exhibited all three types of growth response to hydrogen peroxide, whereas the light-pigmented species M. hiemalis and P. lilacinus showed only the first type of growth response. A concentration of hydrogen peroxide equal to 10(-1) M was found to be lethal to all of the fungi studied. The most resistant to hydrogen peroxide was found to be the strain A. alternata 56, isolated from the exclusion zone of the Chernobyl Nuclear Power Plant.
研究了过氧化氢（10⁻⁹ - 10⁻¹ M）对真菌链格孢、枝孢、冬毛霉和淡紫拟青霉菌丝生长的影响。来自放射性污染背景水平栖息地的真菌，其生长在过氧化氢浓度等于10⁻³ M和10⁻² M时停止，而从高放射性污染栖息地分离出的真菌，其生长仅在10⁻¹ M过氧化氢时才被抑制。不同真菌对过氧化氢的反应有三种类型：（1）在过氧化氢浓度为10⁻⁹至10⁻⁴ M之间时，真菌菌丝的生长速率恒定，在10⁻³ M过氧化氢时该速率下降；（2）随着过氧化氢浓度增加，生长速率逐渐下降；（3）随着过氧化氢浓度从10⁻⁷增加到10²⁻⁵ M，生长速率增加。含黑色素的链格孢和枝孢对过氧化氢表现出所有三种类型的生长反应，而浅色的冬毛霉和淡紫拟青霉仅表现出第一种生长反应。发现10⁻¹ M的过氧化氢浓度对所有研究的真菌都是致命的。发现最耐过氧化氢的是从切尔诺贝利核电站禁区分离出的链格孢56菌株。
