Luyk N H, Zacharias M, Wanwimolaruk S
University of Otago, Dunedin, New Zealand.
Int J Oral Maxillofac Surg. 1992 Jun;21(3):172-5. doi: 10.1016/s0901-5027(05)80788-x.
This double-blind, randomised, cross-over trial in 41 patients for 3rd molar surgery compared the safety, amnesic properties and psychomotor recovery between a bolus injection of midazolam and a bolus injection followed by continuous infusion of midazolam. The latter showed good safety and better amnesia to events during the procedure, but prolonged the recovery time.
这项针对41例患者进行的第三磨牙手术的双盲、随机、交叉试验，比较了单次注射咪达唑仑与单次注射后持续输注咪达唑仑在安全性、遗忘特性和精神运动恢复方面的差异。后者显示出良好的安全性，对手术过程中的事件有更好的遗忘效果，但延长了恢复时间。
