Ben Jannet Hichem, Chaari Atef, Bakhrouf Amina, Mighri Zine
Laboratoire de Chimie des Substances Naturelles et de Synthèse Organique, Faculté des Sciences de Monastir, 5019 Monastir, Tunisia.
Nat Prod Res. 2006 Mar;20(3):299-304. doi: 10.1080/14786410500129129.
A selection of steroids, glycerides, clerodane diterpenoids, and a beta-hydroxy fatty acid methyl ester, all previously isolated from Ajuga pseudoiva leaves, were tested for their antibacterial activity toward three Gram- rods and one Gram+ coccus using the dilution method; MIC values were determined. The results suggested some importance for a free beta-hydroxy group in the fatty acid ester and also in the glycerides and clerodane derivatives; the absolute configurations of the latter, notably at C2, had little influence on activity.
