经病理证实的伴或不伴运动神经元变性的额颞叶痴呆（FTLD）的萎缩模式。
Patterns of atrophy in pathologically confirmed FTLD with and without motor neuron degeneration.
作者信息
Whitwell Jennifer L, Jack Clifford R, Senjem Matthew L, Josephs Keith A
机构信息
Department of Radiology, Mayo Clinic, Rochester, MN 55905, USA.
出版信息
Neurology. 2006 Jan 10;66(1):102-4. doi: 10.1212/01.wnl.0000191395.69438.12.
Abstract
The authors used voxel-based morphometry to compare the patterns of brain atrophy in two variants of pathologically confirmed frontotemporal lobar degeneration (FTLD): FTLD with motor neuron disease (FTLD-MND) and FTLD with ubiquitin-only-immunoreactive neuronal changes (FTLD-U). Patterns of atrophy were distinct and different from each other. A localized pattern of frontal lobe atrophy was found in FTLD-MND with a more widespread pattern of atrophy affecting the frontal and temporal lobes in FTLD-U.
摘要
作者使用基于体素的形态测量法，比较了两种经病理证实的额颞叶痴呆（FTLD）变体中的脑萎缩模式：伴运动神经元病的额颞叶痴呆（FTLD-MND）和仅具有泛素免疫反应性神经元变化的额颞叶痴呆（FTLD-U）。萎缩模式彼此不同且有明显差异。在FTLD-MND中发现额叶局限性萎缩模式，而在FTLD-U中则有更广泛的萎缩模式，累及额叶和颞叶。
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本文引用的文献
1
Magnetic resonance imaging signatures of tissue pathology in frontotemporal dementia.
Arch Neurol. 2005 Sep;62(9):1402-8. doi: 10.1001/archneur.62.9.1402.
2
Comparison of different methodological implementations of voxel-based morphometry in neurodegenerative disease.
Neuroimage. 2005 Jun;26(2):600-8. doi: 10.1016/j.neuroimage.2005.02.005. Epub 2005 Apr 12.
3
Pattern of glucose hypometabolism in frontotemporal dementia with motor neuron disease.
Neurology. 2005 Feb 22;64(4):734-6. doi: 10.1212/01.WNL.0000152047.58767.9D.
4
Frontotemporal lobar degeneration and ubiquitin immunohistochemistry.
Neuropathol Appl Neurobiol. 2004 Aug;30(4):369-73. doi: 10.1111/j.1365-2990.2003.00545.x.
5
Hippocampal sclerosis and ubiquitin-positive inclusions in dementia lacking distinctive histopathology.
Dement Geriatr Cogn Disord. 2004;17(4):342-5. doi: 10.1159/000077168.
6
Clinical and pathological diagnosis of frontotemporal dementia: report of the Work Group on Frontotemporal Dementia and Pick's Disease.
Arch Neurol. 2001 Nov;58(11):1803-9. doi: 10.1001/archneur.58.11.1803.
7
Volumetric analysis reveals corticospinal tract degeneration and extramotor involvement in ALS.
Neurology. 2001 Nov 13;57(9):1571-8. doi: 10.1212/wnl.57.9.1571.
8
Frontotemporal lobar degeneration: a consensus on clinical diagnostic criteria.
Neurology. 1998 Dec;51(6):1546-54. doi: 10.1212/wnl.51.6.1546.
9
A short test of mental status: description and preliminary results.
Mayo Clin Proc. 1987 Apr;62(4):281-8. doi: 10.1016/s0025-6196(12)61905-3.
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