Wild D C, Brewster M J, Banerjee A R
Department of Otorhinolaryngology, Leicester Royal Infirmary, Leicester, UK.
Clin Otolaryngol. 2005 Dec;30(6):517-20. doi: 10.1111/j.1749-4486.2005.01105.x.
To analyse the influence of long-term smoking on the hearing threshold of individuals subjected to occupational noise exposure.
Prospective observational cohort study.
Occupational health examination of noise-exposed employees in the brick manufacturing industry.
A study group of long-term smokers (n = 30) and a control group of non-smokers (n = 58) were identified from a population of 227 male noise-exposed employees. Individuals of both groups were employed for 10 years or more at a single brick manufacturing plant. Data on noise exposure, smoking habits, medical and otological history were collected and standard pure tone audiometry was obtained. Exclusion criteria included asymmetrical or conductive hearing loss, uncontrolled systemic illnesses, history of head injury, chronic middle ear pathology or major ear operations.
Pure tone audiometry.
Both groups had similar mean age and total duration of occupational noise exposure. The median age-corrected hearing thresholds at 3 and 4 kHz in the smokers group were significantly higher (approximately 7dB) than those in the non-smokers group. No statistical difference in the hearing thresholds between both groups was found in any other tested frequency (0.5, 1, 2, 6 and 8 kHz).
Long-term smokers with occupational noise exposure may, on the basis of this limited study, have a higher risk of developing permanent hearing loss at 3 and 4 kHz when compared with non-smokers with a similar occupational history.
分析长期吸烟对遭受职业性噪声暴露个体听力阈值的影响。
前瞻性观察队列研究。
砖制造业噪声暴露员工的职业健康检查。
从227名男性噪声暴露员工中确定了一个长期吸烟者研究组(n = 30)和一个非吸烟者对照组(n = 58)。两组个体均在单一砖厂工作10年或更长时间。收集了噪声暴露、吸烟习惯、病史和耳科病史的数据,并进行了标准纯音听力测定。排除标准包括不对称或传导性听力损失、未控制的全身性疾病、头部受伤史、慢性中耳病变或重大耳部手术史。
纯音听力测定。
两组的平均年龄和职业性噪声暴露总时长相似。吸烟者组在3kHz和4kHz时经年龄校正的听力阈值中位数显著高于非吸烟者组(约7dB)。在其他测试频率(0.5、1、2、6和8kHz)下,两组的听力阈值无统计学差异。
基于这项有限的研究,与有相似职业史的非吸烟者相比,长期遭受职业性噪声暴露的吸烟者在3kHz和4kHz时发生永久性听力损失的风险可能更高。