Rintala R, Mildh L, Lindahl H
Children's Hospital, University of Helsinki, Finland.
J Pediatr Surg. 1992 Jul;27(7):902-5. doi: 10.1016/0022-3468(92)90394-m.
Fecal continence and quality of life were evaluated by a questionnaire in 83 adult patients (mean age, 35 years; 53 women, 30 men) who underwent surgery for a low anorectal anomaly between 1947 and 1963. Fecal continence was assessed by a score described by Holschneider. Seventy-eight healthy people with similar age and sex distributions were used as controls. All controls had good fecal continence, 76% with completely normal bowel function. The aberrations in anal function found in 24% of the controls were minor, such as constipation or occasional slight smearing. Only 60% of the patients who had a low anorectal anomaly had good continence and completely normal bowel function was observed in 15%. Male patients had a slightly better outcome than females. Social problems related to deficient fecal control were reported by 39% of the patients. In addition, 13% of the patients had difficulties in sexual functions. Other health problems were reported by 52% of the patients. Social or sexual problems associated with anal function were not reported by the control population; 6% of them had other health problems. The present controlled study shows that at the adult age, a significant proportion of patients with low anorectal anomalies suffer from deficient fecal control and a diminished quality of life.
采用问卷调查的方式，对1947年至1963年间因低位肛门直肠畸形接受手术的83例成年患者（平均年龄35岁；女性53例，男性30例）的大便失禁情况和生活质量进行了评估。大便失禁情况采用霍尔施奈德描述的评分系统进行评估。选取78例年龄和性别分布相似的健康人作为对照。所有对照者大便控制良好，76%的人肠道功能完全正常。24%的对照者存在轻微的肛门功能异常，如便秘或偶尔轻微的粪便污染。只有60%的低位肛门直肠畸形患者大便控制良好，15%的患者肠道功能完全正常。男性患者的预后略好于女性。39%的患者报告了与大便控制不足相关的社会问题。此外，13%的患者存在性功能障碍。52%的患者报告了其他健康问题。对照人群未报告与肛门功能相关的社会或性功能问题；6%的对照者存在其他健康问题。目前的对照研究表明，在成年期，相当一部分低位肛门直肠畸形患者存在大便控制不足和生活质量下降的问题。
