Seferian Edward G, Henry Nancy K, Wylam Mark E
Department of Pediatric and Adolescent Medicine, Division of Pediatric Critical Care Medicine, Mayo Clinic College of Medicine, Rochester, MN 55905, USA.
Respir Med. 2006 Aug;100(8):1466-9. doi: 10.1016/j.rmed.2005.11.015. Epub 2006 Jan 5.
Infants with cystic fibrosis (CF) may develop severe respiratory compromise related to viral lower respiratory tract infections due to impaired mucous clearance and plugging of small airways. Consequently air trapping may lead to lung hyperinflation, impaired gas exchange, and respiratory failure. We describe the case of an infant with newly diagnosed CF who developed severe hypercarbic respiratory failure in the setting of viral bronchiolitis successfully treated with high-frequency oscillatory ventilation (HFOV).
患有囊性纤维化（CF）的婴儿可能会因黏液清除功能受损和小气道堵塞而出现与病毒性下呼吸道感染相关的严重呼吸功能不全。因此，气体潴留可能导致肺过度充气、气体交换受损和呼吸衰竭。我们描述了一例新诊断为CF的婴儿病例，该婴儿在病毒性细支气管炎的情况下发展为严重的高碳酸血症性呼吸衰竭，并通过高频振荡通气（HFOV）成功治疗。
