Gutiérrez-Macías Alfonso, Lizarralde-Palacios Eva, Martínez-Odriozola Pedro, Miguel-de la Villa Felipe
Internal Medicine Department, Hospital de Basurto, Avenida de Montevideo, 18, 48013 Bilbao, Spain.
Clin Rheumatol. 2007 Mar;26(3):452-3. doi: 10.1007/s10067-005-0164-3. Epub 2006 Jan 11.
We present a case of tuberculous peritonitis in a 71-year-old woman with long-standing rheumatoid arthritis treated with adalimumab, and we review the association between antitumor necrosis factor therapy and tuberculosis. Our case illustrates that the index of suspicion of tuberculosis in these patients, even with atypical clinical features, must be very high, and underscores the need of tuberculosis screening before therapy is started.
我们报告一例71岁患有长期类风湿关节炎且接受阿达木单抗治疗的女性结核性腹膜炎病例,并回顾抗肿瘤坏死因子治疗与结核病之间的关联。我们的病例表明,即使这些患者临床特征不典型,对结核病的怀疑指数也必须非常高,并强调在开始治疗前进行结核病筛查的必要性。