[Alkaloids from the root of Lindera angustifolia].

AIM

To study the alkaloid constituents of the root of Lindera angustifolia Cheng.

METHODS

The constituents were isolated and purified by column chromatography and the structures were characterized by spectral analysis.

RESULTS

Seven aporphine alkaloids, laurotetanine (I), N-methyllaurotetanine (II), boldine (III), isoboldine (IV), norboldine (V), N-ethoxycarbonyllaurotetanine (VII) and a quaternary isoquinoline alkaloid, magnocurarine (VI), were isolated and identified. The structure of VII was further identified by semi-synthesis with I as starting material.

CONCLUSION

All compounds were obtained from this plant for the first time and compound VII was found as a naturally occurring compound for the first time.