Kalgutkar Alka, Kini Sangeeta, Jambhekar Nirmala, Das Sutapa
Department of Pathology, Lokmanya Tilak Municipal Medical College and General Hospital, Sion, Mumbai 400022, India.
Ann Diagn Pathol. 2006 Feb;10(1):20-3. doi: 10.1016/j.anndiagpath.2005.07.007.
Intradiploic inclusion cyst of the skull presenting as a calvarial defect is fairly uncommon in the neuroscience practice. They are benign in nature, slow to grow, and clinically difficult to differentiate from other causes of calvarial defects. We present a case of a healthy 55-year-old woman who presented clinically for an asymptomatic lump over the right parieto-occipital region of the scalp of 4-month duration. The radiological features were suggestive of presence of a large intradiploic solitary cyst and additional multiple lytic defects with sclerotic borders, destroying the underlying bone. The gross and histomorphological features of the right parieto-occipital craniectomy specimen received were pathognomic of an intradiploic primary epithelial inclusion cyst of the skull bone. The importance of its benign nature, embryogenic origin, and differentiation from other cystic lesions with similar histology is stressed. We report this case for its unique histomorphology and first of its kind in the Indian literature.
颅骨板障内包涵囊肿表现为颅骨缺损在神经科学实践中相当少见。它们本质上是良性的，生长缓慢，临床上难以与其他导致颅骨缺损的原因相鉴别。我们报告一例健康的55岁女性，临床上因右顶枕部头皮出现一个持续4个月的无症状肿块前来就诊。影像学特征提示存在一个大的板障内孤立囊肿以及额外的多个边界硬化的溶骨性缺损，破坏了下方的骨质。所接收的右顶枕部颅骨切除术标本的大体和组织形态学特征符合颅骨板障原发性上皮包涵囊肿的特征。强调了其良性本质、胚胎起源以及与其他具有相似组织学的囊性病变相鉴别的重要性。我们报告该病例是因其独特的组织形态学，且在印度文献中尚属首例。
