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耳廓鳞状细胞癌与莫氏显微外科手术

Squamous cell carcinoma of the auricle and Mohs micrographic surgery.

作者信息

Silapunt Sirunya, Peterson S Ray, Goldberg Leonard H

机构信息

DermSurgery Associates, Houston, Texas 77030, USA.

出版信息

Dermatol Surg. 2005 Nov;31(11 Pt 1):1423-7. doi: 10.2310/6350.2005.31208.

DOI:10.2310/6350.2005.31208
PMID:16416611
Abstract

BACKGROUND

Squamous cell carcinoma (SCC) of the ear compared with SCC occurring at other skin sites has an increased incidence of recurrence following treatment.

OBJECTIVE

To determine the following variables: patient age and gender, life status, tumor location, and recurrence rate following Mohs micrographic surgery (MMS).

METHODS

The charts of 117 patients with 144 invasive SCCs of the auricle were reviewed. The patients were contacted by telephone to confirm tumor recurrence and patients' life status. The range of follow-up was 7 to 67 months (average 34.6 months) after MMS.

RESULTS

The patients' ages ranged from 34 to 90 years (mean age 71 years). The male to female ratio was 22:1. The helix was the most common site of occurrence (50.7%). Local recurrence after MMS was found in four patients (five tumors). MMS was performed on these five recurrent tumors, with no further recurrences. Telephone confirmation was obtained on 91 patients (26 patients could not be contacted) with 122 tumors, which included the 4 patients with 5 recurrent tumors. There were no additional recurrences. Of these 122 tumors, 35 were followed for less than 2 years (average 16.6 months), and 87 were followed for 2 years or more (average 41.8 months). From the chart review and telephone contact, the 2-year local recurrence rate was 5.7% (5 of 87 tumors) after MMS. The average size of these 87 tumors was 3.5 cm2. Twelve of 91 patients had died with evidence of active disease from causes unrelated to SCC.

CONCLUSION

Invasive SCC of the ear was once a formidable disease with a severe prognosis. The course of this disease has been appreciably improved by early diagnosis and treatment with MMS.

摘要

背景

耳部鳞状细胞癌(SCC)与发生于其他皮肤部位的SCC相比,治疗后复发率更高。

目的

确定以下变量:患者年龄和性别、生活状况、肿瘤位置以及莫氏显微外科手术(MMS)后的复发率。

方法

回顾了117例患有144例耳廓浸润性SCC患者的病历。通过电话联系患者以确认肿瘤复发情况和患者生活状况。MMS后随访时间为7至67个月(平均34.6个月)。

结果

患者年龄在34至90岁之间(平均年龄71岁)。男女比例为22∶1。耳轮是最常见的发病部位(50.7%)。4例患者(5个肿瘤)在MMS后出现局部复发。对这5个复发性肿瘤进行了MMS,未再复发。对91例患者(26例无法联系到)的122个肿瘤进行了电话确认,其中包括4例有5个复发性肿瘤的患者。无其他复发情况。在这122个肿瘤中,35个随访时间少于2年(平均16.6个月),87个随访时间为2年或更长(平均41.8个月)。通过病历回顾和电话联系,MMS后2年局部复发率为5.7%(87个肿瘤中的5个)。这87个肿瘤的平均大小为3.5平方厘米。91例患者中有12例死于与SCC无关的活动性疾病。

结论

耳部浸润性SCC曾经是一种预后严重的可怕疾病。通过早期诊断和MMS治疗,该病的病程已得到明显改善。

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