Carruthers Alastair, Carruthers Jean D A
Division of Dermatology, University of British Columbia, Vancouver, British Columbia, Canada.
Dermatol Surg. 2005 Nov;31(11 Pt 2):1561-4; discussion 1565. doi: 10.2310/6350.2005.31242.
Polymethylmethacrylate microspheres/collagen has been used in Canada since 1998. A closely related product will probably be approved in the United States shortly. Concerns have been expressed about the use of permanent fillers such as this.
This retrospective study of the authors' clinical practice is designed to reflect their experience with this agent. In particular, the authors describe some of the problems they have seen.
Polymethylmethacrylate microspheres/collagen has behaved as a satisfactory long-term tissue augmenting agent in the authors' practice. They have had the opportunity of managing any number of patients with Artecoll granulomas and describe these patients.
When polymethylmethacrylate microspheres/collagen is introduced to the United States, practitioners will need to learn how to use this exacting agent and will obtain excellent results with careful use.
自1998年以来，聚甲基丙烯酸甲酯微球/胶原蛋白已在加拿大使用。一种密切相关的产品可能很快会在美国获批。人们对使用此类永久性填充剂表示担忧。
这项对作者临床实践的回顾性研究旨在反映他们使用该制剂的经验。特别是，作者描述了他们所见到的一些问题。
在作者的实践中，聚甲基丙烯酸甲酯微球/胶原蛋白已表现为一种令人满意的长期组织填充剂。他们有机会处理大量接受爱贝芙治疗后出现肉芽肿的患者，并对这些患者进行了描述。
当聚甲基丙烯酸甲酯微球/胶原蛋白引入美国时，从业者将需要学习如何使用这种严格的制剂，谨慎使用将获得良好效果。
