Lee D M
Medizinische Abteilung für Ernährung und Stoffwechsel, Heinrich-Heine-Universität, Düsseldorf.
Z Gesamte Inn Med. 1992 Jun;47(6):266-9.
Injection-pain was assessed in 39 type-1 diabetic patients in relation to an insulin injection (with an insulin-pen) into the upper arm, the abdomen, and the thigh and in another 10 patients, pain associated with finger-pricking for blood-glucose self-monitoring was assessed. Pain perception was recorded on a visual analogue scale. According to the results, injections were relatively painless with an average (median) pain-score of less than 10% of maximum pain. Injection pains varied in relation to the injection sites (upper arm greater than thigh greater than abdomen). Least painful (n = 44) versus most painful (n = 39) injections were distributed as follows: upper arm 20% vs. 46%, abdomen 43% vs. 23%, thigh 36% vs. 31% (chi 2 7.26, df2, p less than 0.05). Finger-pricking was no more painful than injecting insulin. It is concluded that insulin injecting (e.g. with insulin pens) and blood glucose self-monitoring in general is not very painful. However, if this positive conclusion also applies to long-term performance of intensive insulin therapy remains to be proven.
对39名1型糖尿病患者进行了胰岛素注射疼痛评估,评估内容为使用胰岛素笔在上臂、腹部和大腿进行胰岛素注射时的疼痛情况;另外还对10名患者进行了指尖采血进行血糖自我监测时的疼痛评估。疼痛感知通过视觉模拟量表进行记录。结果显示,注射相对无痛,平均(中位数)疼痛评分低于最大疼痛的10%。注射疼痛因注射部位而异(上臂>大腿>腹部)。最不痛(n = 44)与最痛(n = 39)的注射分布如下:上臂分别为20%和46%,腹部分别为43%和23%,大腿分别为36%和31%(χ² = 7.26,自由度 = 2,p<0.05)。指尖采血并不比注射胰岛素更痛。结论是,一般来说,胰岛素注射(如使用胰岛素笔)和血糖自我监测并不是非常疼痛。然而,这一积极结论是否也适用于强化胰岛素治疗的长期效果仍有待证实。