Lee D M
Medizinische Abteilung für Ernährung und Stoffwechsel, Heinrich-Heine-Universität, Düsseldorf.
Z Gesamte Inn Med. 1992 Jun;47(6):266-9.
Injection-pain was assessed in 39 type-1 diabetic patients in relation to an insulin injection (with an insulin-pen) into the upper arm, the abdomen, and the thigh and in another 10 patients, pain associated with finger-pricking for blood-glucose self-monitoring was assessed. Pain perception was recorded on a visual analogue scale. According to the results, injections were relatively painless with an average (median) pain-score of less than 10% of maximum pain. Injection pains varied in relation to the injection sites (upper arm greater than thigh greater than abdomen). Least painful (n = 44) versus most painful (n = 39) injections were distributed as follows: upper arm 20% vs. 46%, abdomen 43% vs. 23%, thigh 36% vs. 31% (chi 2 7.26, df2, p less than 0.05). Finger-pricking was no more painful than injecting insulin. It is concluded that insulin injecting (e.g. with insulin pens) and blood glucose self-monitoring in general is not very painful. However, if this positive conclusion also applies to long-term performance of intensive insulin therapy remains to be proven.
对39名1型糖尿病患者进行了胰岛素注射疼痛评估，评估内容为使用胰岛素笔在上臂、腹部和大腿进行胰岛素注射时的疼痛情况；另外还对10名患者进行了指尖采血进行血糖自我监测时的疼痛评估。疼痛感知通过视觉模拟量表进行记录。结果显示，注射相对无痛，平均（中位数）疼痛评分低于最大疼痛的10%。注射疼痛因注射部位而异（上臂＞大腿＞腹部）。最不痛（n = 44）与最痛（n = 39）的注射分布如下：上臂分别为20%和46%，腹部分别为43%和23%，大腿分别为36%和31%（χ² = 7.26，自由度 = 2，p＜0.05）。指尖采血并不比注射胰岛素更痛。结论是，一般来说，胰岛素注射（如使用胰岛素笔）和血糖自我监测并不是非常疼痛。然而，这一积极结论是否也适用于强化胰岛素治疗的长期效果仍有待证实。
