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2
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本文引用的文献

1
Evaluating mortality in intensive care units: contribution of competing risks analyses.评估重症监护病房的死亡率:竞争风险分析的作用。
Crit Care. 2006 Feb;10(1):R5. doi: 10.1186/cc3921.
2
Randomized, placebo-controlled trial of lisofylline for early treatment of acute lung injury and acute respiratory distress syndrome.利索茶碱用于急性肺损伤和急性呼吸窘迫综合征早期治疗的随机、安慰剂对照试验。
Crit Care Med. 2002 Jan;30(1):1-6. doi: 10.1097/00003246-200201000-00001.
3
Nonparametric estimation in a cure model with random cure times.具有随机治愈时间的治愈模型中的非参数估计。
Biometrics. 2001 Mar;57(1):282-6. doi: 10.1111/j.0006-341x.2001.00282.x.
4
Effect of a protective-ventilation strategy on mortality in the acute respiratory distress syndrome.保护性通气策略对急性呼吸窘迫综合征死亡率的影响。
N Engl J Med. 1998 Feb 5;338(6):347-54. doi: 10.1056/NEJM199802053380602.
5
Analysing survival in the presence of an auxiliary variable.在存在辅助变量的情况下分析生存情况。
Stat Med. 1994 Sep 15;13(17):1747-54. doi: 10.1002/sim.4780131706.
6
Properties of proportional-hazards score tests under misspecified regression models.错误设定回归模型下比例风险评分检验的性质。
Biometrics. 1984 Dec;40(4):1037-48.

生存方法,包括那些使用竞争风险分析的方法,不适用于重症监护病房结局研究。

Survival methods, including those using competing risk analysis, are not appropriate for intensive care unit outcome studies.

作者信息

Schoenfeld David

机构信息

Harvard Medical School, Massachusetts General Hospital Biostatistics Center, Staniford Street, Boston, MA 02114, USA.

出版信息

Crit Care. 2006 Feb;10(1):103. doi: 10.1186/cc3949.

DOI:10.1186/cc3949
PMID:16420653
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1550820/
Abstract

The preferred analysis for studies of mortality among patients treated in an intensive care unit should compare the proportions of patients who died during hospitalization. Studies that look for prognostic covariates should use logistic regression. Survival methods, such as the proportional hazards model, or methods based on competing risk analysis are not appropriate because prolonged survival among patients that die during their hospitalization does not benefit the patient and, therefore, should not be measured in the statistical analysis.

摘要

对重症监护病房接受治疗的患者进行死亡率研究时,首选的分析方法应是比较住院期间死亡患者的比例。寻找预后协变量的研究应使用逻辑回归。生存方法,如比例风险模型或基于竞争风险分析的方法并不适用,因为在住院期间死亡的患者延长生存时间对患者并无益处,因此在统计分析中不应进行衡量。