Jimenez Nathalia, Bradford Heidi, Seidel Kristy D, Sousa Manuela, Lynn Anne M
Department of Anesthesiology and Pain Medicine, Children's Hospital and Regional Medical Center, University of Washington School of Medicine, Seattle, WA 98105, USA.
Anesth Analg. 2006 Feb;102(2):411-4. doi: 10.1213/01.ane.0000194293.10549.62.
Placement of IV catheters is a painful and stressful procedure for children. J-Tip is a needle-less Food and Drug Administration approved injection system that can be used for delivery of local anesthetic before IV cannulation. In this study, we compared the effectiveness of J-Tip versus eutectic mixture of local anesthetics (EMLA) to facilitate IV cannulation and provide adequate analgesia before IV placement. Children 7-19 years of age (n = 116) were randomized to receive 0.25 mL of 1% buffered lidocaine with J-Tip (n = 57) or 2.5 g of EMLA (n = 59) before IV cannulation. Measurements of success of cannulation (number of attempts for IV placement) and pain (0-10 visual analog scale) at application of local anesthetic and at cannulation were performed. There was a significant (P = 0.0001) difference in pain ratings during IV cannulation between EMLA (median = 3) and the J-Tip (median = 0). Eighty-four percent of patients reported no pain at the time of J-Tip lidocaine application compared to 61% in the EMLA group at the time of dressing removal (P = 0.004). We did not find differences in the number of attempts for IV cannulation. J-Tip application of 1% buffered lidocaine before IV cannulation is not painful and has better anesthetic effectiveness compared with EMLA.
对儿童而言,静脉留置针穿刺是一个痛苦且有压力的过程。J-Tip是一种经美国食品药品监督管理局批准的无针注射系统,可用于在静脉插管前注射局部麻醉剂。在本研究中,我们比较了J-Tip与局部麻醉剂共熔混合物(EMLA)在促进静脉插管以及在静脉穿刺前提供充分镇痛方面的效果。将7至19岁的儿童(n = 116)随机分为两组,在静脉插管前,一组接受使用J-Tip注射0.25 mL 1%的缓冲利多卡因(n = 57),另一组接受涂抹2.5 g EMLA(n = 59)。分别测量了局部麻醉剂应用时和插管时的插管成功率(静脉穿刺尝试次数)和疼痛程度(采用0至10分视觉模拟评分法)。在静脉插管过程中,EMLA组(中位数 = 3)和J-Tip组(中位数 = 0)的疼痛评分存在显著差异(P = 0.0001)。84%的患者在使用J-Tip利多卡因时表示无疼痛,而在EMLA组,去除敷料时这一比例为61%(P = 0.004)。我们未发现两组在静脉插管尝试次数上存在差异。在静脉插管前应用1%的缓冲利多卡因,采用J-Tip注射法无痛且与EMLA相比具有更好的麻醉效果。