Schoenfelder Renate C, Ponnamma Chandra M, Freyle David, Wang Shu-Ming, Kain Zeev N
Center for the Advancement of Perioperative Health, Yale University School of Medicine, New Haven, Connecticut 06520-8051, USA.
Anesth Analg. 2006 Feb;102(2):415-7. doi: 10.1213/01.ane.0000189218.07293.6e.
In this study we sought to determine if chewing gum preoperatively increases gastric fluid volume (GFV) and changes gastric acidity. Children, 5-17 yr old, were randomized to one of three groups: a control group that was not given any gum, a group that was given sugarless bubble gum, and a group that was given sugared bubble gum. Patients in the two gum groups were instructed to chew their gum for a period of 30 min. After induction of anesthesia and tracheal intubation, the stomach was suctioned with a salem sump orogastric tube. We found that children who did not chew gum had significantly smaller GFV as compared with children who chewed sugared and sugarless gum (0.35 [0.2-0.5] mL/kg versus 0.88 [0.6-1.4] mL/kg versus 0.69 [0.4-1.6] mL/kg; P = 0.0001). Children who did not chew gum also had a significantly lower gastric fluid pH as compared with children chewing sugared and sugarless gum (geometric mean, 1.91 versus 2.25 versus 2.19; P = 0.007). We conclude that children who present for surgery while chewing gum have significantly larger GFV and higher pH.
在本研究中，我们试图确定术前咀嚼口香糖是否会增加胃液量（GFV）并改变胃酸度。将5至17岁的儿童随机分为三组之一：未给予任何口香糖的对照组、给予无糖泡泡糖的组和给予含糖泡泡糖的组。两个口香糖组的患者被指示咀嚼口香糖30分钟。在诱导麻醉和气管插管后，用塞勒姆水槽口胃管抽吸胃内容物。我们发现，与咀嚼含糖和无糖口香糖的儿童相比，未咀嚼口香糖的儿童的GFV明显更小（0.35 [0.2 - 0.5] mL/kg 对比 0.88 [0.6 - 1.4] mL/kg 对比 0.69 [0.4 - 1.6] mL/kg；P = 0.0001）。与咀嚼含糖和无糖口香糖的儿童相比，未咀嚼口香糖的儿童的胃液pH值也明显更低（几何平均值，1.91对比2.25对比2.19；P = 0.007）。我们得出结论，手术时咀嚼口香糖的儿童的GFV明显更大，pH值更高。
