Byrne Carolyn, Browne Gina, Roberts Jacqueline, Mills Michael, Bell Barbara, Gafni Amiram, Jamieson Ellen, Webb Michelle
Dr. Byrne is with the University of Ontario Institute of Technology, Faculty of Health Sciences, Oshawa, and McMaster University's Faculty of Health Sciences System-Linked Research Unit on Health and Social Service Utilization, Hamilton; Drs. Browne and Roberts are with McMaster University's System-Linked Research Unit on Health and Social Service Utilization and the Department of Clinical Epidemiology and Biostatistics; Drs. Mills and Bell are with the Caroline Medical Group, Burlington; Dr. Gafni is with McMaster University's Faculty of Health Sciences Department of Clinical Epidemiology and Biostatistics, Centre for Health Economics and Policy Analysis, and System-Linked Research Unit on Health and Social Service Utilization; Ms. Jamieson and Ms. Webb are with McMaster University's System-Linked Research Unit on Health and Social Service Utilization, Hamilton.
Dr. Byrne is with the University of Ontario Institute of Technology, Faculty of Health Sciences, Oshawa, and McMaster University's Faculty of Health Sciences System-Linked Research Unit on Health and Social Service Utilization, Hamilton; Drs. Browne and Roberts are with McMaster University's System-Linked Research Unit on Health and Social Service Utilization and the Department of Clinical Epidemiology and Biostatistics; Drs. Mills and Bell are with the Caroline Medical Group, Burlington; Dr. Gafni is with McMaster University's Faculty of Health Sciences Department of Clinical Epidemiology and Biostatistics, Centre for Health Economics and Policy Analysis, and System-Linked Research Unit on Health and Social Service Utilization; Ms. Jamieson and Ms. Webb are with McMaster University's System-Linked Research Unit on Health and Social Service Utilization, Hamilton.
J Am Acad Child Adolesc Psychiatry. 2006 Feb;45(2):239-246. doi: 10.1097/01.chi.0000190351.13818.d7.
This study examined differences in children's behavior and expenditures for health and social services used when their parents with dysthymia did or did not respond to antidepressant therapy.
Children ages 4 to 16 years of consenting parents enrolled in a treatment trial for dysthymia who did and did not respond to treatment were compared at baseline and 24 months. The responder was a parent with at least a 40% reduction in his or her baseline depressive symptoms using the Montgomery Asberg Depression Rating Scale. Children's behavior was measured using the Child Behavior Checklist, and expenditures for health and social services use was measured in Canadian dollars using the Health and Social Service Utilization Questionnaire.
Children of parents with dysthymia who responded to treatment had significantly greater reductions in emotional symptoms at 2-year follow-up than children of nonresponders, along with an economically important (not statistically significant) reduction in expenditures for health and social services use.
Reductions in parental symptoms of dysthymia may be associated with reductions in childhood behavioral problems and in expenditures for the child's use of services.
本研究探讨了患有心境恶劣障碍的父母接受或未接受抗抑郁治疗时，其子女的行为以及用于健康和社会服务的支出差异。
对年龄在4至16岁、其父母同意参与心境恶劣障碍治疗试验且治疗有反应和无反应的儿童，在基线和24个月时进行比较。有反应者是指使用蒙哥马利-阿斯伯格抑郁评定量表，其基线抑郁症状至少减轻40%的父母。使用儿童行为清单测量儿童行为，使用健康和社会服务利用问卷以加拿大元测量健康和社会服务使用的支出。
接受治疗有反应的心境恶劣障碍父母的子女，在2年随访时情绪症状的减轻程度显著大于无反应者的子女，同时在健康和社会服务使用支出方面有经济上重要的（无统计学显著性）减少。
心境恶劣障碍父母症状的减轻可能与儿童行为问题的减少以及儿童使用服务的支出减少有关。
