Grulois V, Buysschaert I, Schoenaers J, Debruyne F, Delaere P, Vander Poorten V
Department of ENT and Head and Neck Surgery, University Hospitals Saint-Luc, Brussels, Belgium.
B-ENT. 2005;1(4):191-5.
The skeletal lesions of primary hyperparathyroidism, including brown tumour, are rare nowadays, with the practice of checking serum calcium levels leading to an earlier diagnosis of hyperparathyroidism. Clinical, laboratory, radiographic and histological investigations can lead to a correct diagnosis. Treatment of brown tumour focuses on the hyperparathyroidism, and is usually followed by a regression of the brown tumour. The diagnosis of hyperparathyroidism and brown tumour should be considered in patients with hypercalcaemia and an osteolytic expansive bone lesion. We present a patient where a brown tumour of the mandible was the presenting symptom of primary hyperparathyroidism.
如今,原发性甲状旁腺功能亢进症的骨骼病变,包括棕色瘤,已较为罕见,因为现在会检查血清钙水平,从而能更早诊断出甲状旁腺功能亢进症。临床、实验室、影像学和组织学检查有助于做出正确诊断。棕色瘤的治疗重点在于甲状旁腺功能亢进症,通常在治疗后棕色瘤会消退。对于高钙血症和溶骨性膨胀性骨病变的患者,应考虑诊断为甲状旁腺功能亢进症和棕色瘤。我们报告了一例患者,其下颌骨棕色瘤是原发性甲状旁腺功能亢进症的首发症状。