Turbes C C
Division of Anatomy, Creighton University, Omaha, NE 68178.
Biomed Sci Instrum. 1992;28:59-67.
Oscillation and resonance of electrical activity of certain sets of neurons in the brain and spinal cord is an important factor in the organization of those properties of connectivity that must be tuned by function. Once connectivity has reached some degree of specificity important biological and chemical events must occur to stabilize synaptic inputs and localize excitable sites to particular areas of the cell surface. It has been proposed that intrinsic electroresponsiveness generates internal computational states that serves as a reference frame or context for incoming information. The intrinsic activity is proposed to be a part of the vectorial coordinate space that sensory and motor transformations occur in context of a particular functional state such as attention and expectation that can modify the relevance of a given sensory input. The most significant mechanism in generation of oscillation properties of the brain are the intrinsic properties of individual neurons. This concept presents a shift of emphasis from properties of circuits to properties of single neurons. Feedback circuits and synchronization of single oscillators into sets of coupled oscillators which in turn generates field potentials such as (EEG) and evoked response (ER).
大脑和脊髓中某些神经元组的电活动振荡与共振,是那些必须通过功能进行调节的连接特性组织中的一个重要因素。一旦连接达到某种程度的特异性,就必须发生重要的生物和化学事件,以稳定突触输入并将可兴奋位点定位到细胞表面的特定区域。有人提出,内在电反应性会产生内部计算状态,这些状态可作为传入信息的参考框架或背景。内在活动被认为是矢量坐标空间的一部分,在诸如注意力和期望等特定功能状态的背景下,感觉和运动转换会在此空间中发生,而这些功能状态可以改变给定感觉输入的相关性。大脑振荡特性产生的最重要机制是单个神经元的内在特性。这一概念将重点从电路特性转移到了单个神经元的特性上。反馈电路以及单个振荡器同步成耦合振荡器组,进而产生诸如(脑电图)和诱发反应(ER)等场电位。