Leclerc Henri
l'Académie nationale de médecine, Faculté de médecine, pôle recherche, I place de Verdun, 59045, Lille cedex.
Bull Acad Natl Med. 2005 Jun;189(6):1221-33; discussion 1233-4.
Water is the main reservoir for legionellae, and these bacteria are found in freshwater environments worldwide. Legionellae survive in aquatic and moist soil environments, in biofilms, as intracellular parasites of free-living protozoa. Protozoa naturally present in the environment support the intracellular growth of legionellae in vitro. Much of our understanding of the pathogenesis of legionellosis is based on studies of the infective process in protozoa and human cells.
水是军团菌的主要储存库，这些细菌在世界各地的淡水环境中都能找到。军团菌在水生和潮湿的土壤环境、生物膜以及作为自由生活原生动物的细胞内寄生虫中生存。环境中天然存在的原生动物支持军团菌在体外的细胞内生长。我们对军团菌病发病机制的许多理解都基于对原生动物和人类细胞感染过程的研究。
