Cho N H, Ahn C W, Park J Y, Ahn T Y, Lee H W, Park T S, Kim I J, Pomerantz K, Park C, Kimm K C, Choi D S
Department of Internal Medicine, Yonsei University, Seoul, Korea.
Diabet Med. 2006 Feb;23(2):198-203. doi: 10.1111/j.1464-5491.2005.01789.x.
We investigated the prevalence and risk factors for developing erectile dysfunction (ED) in 1312 Korean men with diabetes in a multicentre study.
We used the modified International Index for Erectile Function-5 criteria to identify mild, moderate and complete ED. A standardized face-to-face questionnaire was used by trained interviewers, and validated against telephone interviews. We recorded the duration of diabetes, level of glycaemic control, vital signs, complications, exercise and alcohol and smoking habits, and diabetes treatments used. Results The mean age and median duration of diabetes were 53.8 +/- 6.65 and 6 years (range 1-43), respectively. The mean HbA(1c) and fasting glucose levels were 7.9 +/- 1.65% and 8.6 +/- 2.82 mmol/l, respectively. The overall prevalences of mild, moderate, complete ED and all ED (mild-to-complete) were 20.1, 19.5, 25.8 and 65.4%, respectively. ED was more common with age, reaching 79.3% in men aged > 60 years. Subjects aged > 60 years and with a duration of diabetes > 10 years were at greatest risk for all ED (OR = 10.4, 95% CI 5.8-18.5, P < 0.001) and complete ED (OR = 13.2, 95% CI 7.3-23.9, P < 0.001) when compared with the reference group (age 40-50 years with duration < 6 years). Age, duration of diabetes, HbA(1c), insulin use, neuropathy and macrovascular complications were positively associated with ED, but alcohol consumption and exercise habits were negatively associated.
The prevalence of complete ED was approximately six times higher than in the general population.
在一项多中心研究中，我们调查了1312名韩国糖尿病男性勃起功能障碍（ED）的患病率及其危险因素。
我们采用改良的国际勃起功能指数-5标准来确定轻度、中度和重度ED。由经过培训的访谈者使用标准化的面对面问卷，并通过电话访谈进行验证。我们记录了糖尿病病程、血糖控制水平、生命体征、并发症、运动及饮酒和吸烟习惯，以及所使用的糖尿病治疗方法。结果糖尿病患者的平均年龄和病程中位数分别为53.8±6.65岁和6年（范围1 - 43年）。平均糖化血红蛋白（HbA1c）水平和空腹血糖水平分别为7.9±1.65%和8.6±2.82 mmol/L。轻度、中度、重度ED及所有ED（轻度至重度）的总体患病率分别为20.1%、19.5%、25.8%和65.4%。ED随年龄增长更为常见，60岁以上男性中ED患病率达79.3%。与参照组（年龄40 - 50岁，病程<6年）相比，60岁以上且糖尿病病程>10年的受试者发生所有ED（比值比[OR]=10.4，95%置信区间[CI] 5.8 - 18.5，P<0.001）和重度ED（OR = 13.2，95% CI 7.3 - 23.9，P<0.001）的风险最高。年龄、糖尿病病程、HbA1c、胰岛素使用、神经病变和大血管并发症与ED呈正相关，而饮酒和运动习惯与ED呈负相关。
重度ED的患病率约比普通人群高六倍。
