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含铁血黄素沉着性及动脉瘤样皮肤纤维瘤的皮肤镜表现:6例患者报告

Dermoscopic findings of haemosiderotic and aneurysmal dermatofibroma: report of six patients.

作者信息

Zaballos P, Llambrich A, Ara M, Olazarán Z, Malvehy J, Puig S

机构信息

Dermatology Department, Hospital de Sant Pau i Santa Tecla, Rambla Vella, 14, 43003 Tarragona, Spain.

出版信息

Br J Dermatol. 2006 Feb;154(2):244-50. doi: 10.1111/j.1365-2133.2005.06844.x.

DOI:10.1111/j.1365-2133.2005.06844.x
PMID:16433792
Abstract

BACKGROUND

The clinical diagnosis of dermatofibroma is commonly easy. However, the differentiation of dermatofibroma from other cutaneous tumours is difficult in some instances, primarily in atypical cases and rare variants. Haemosiderotic dermatofibroma is a variant composed of numerous small vessels, extravasated erythrocytes and intra- and extracellular haemosiderin deposits. Aneurysmal dermatofibroma is a variant composed of large, blood-filled spaces without endothelial lining. Some authors consider that haemosiderotic dermatofibroma is an early stage in the development of aneurysmal dermatofibroma. The clinical differential diagnosis of haemosiderotic or aneurysmal dermatofibroma must include melanoma and other melanocytic tumours, vascular neoplasms, adnexal tumours and nonspecific cysts. Dermoscopy improves the diagnostic accuracy in pigmented and nonpigmented skin lesions.

OBJECTIVES

To evaluate specific dermoscopic criteria.

METHODS

Dermoscopic examination (using the DermLite Foto; 3Gen, LLC, Dana Point, CA, U.S.A.) of six patients with haemosiderotic or aneurysmal dermatofibromas was performed to evaluate specific dermoscopic criteria.

RESULTS

A multicomponent pattern with a central bluish or reddish homogeneous area in combination with white structures and a peripheral delicate pigment network along with vascular structures was noted in five of six lesions.

CONCLUSIONS

This dermoscopic pattern yielded the diagnosis of haemosiderotic or aneurysmal dermatofibroma in most cases. However, this multicomponent pattern may present in some melanomas and although it is useful in determining a clinical diagnosis of aneurysmal dermatofibroma, it may not be specific to this entity.

摘要

背景

皮肤纤维瘤的临床诊断通常较为容易。然而,在某些情况下,尤其是非典型病例和罕见变体中,将皮肤纤维瘤与其他皮肤肿瘤区分开来却很困难。含铁血黄素性皮肤纤维瘤是一种由众多小血管、外渗红细胞以及细胞内和细胞外含铁血黄素沉积组成的变体。动脉瘤样皮肤纤维瘤是一种由无内皮衬里的大的充血腔隙组成的变体。一些作者认为含铁血黄素性皮肤纤维瘤是动脉瘤样皮肤纤维瘤发展的早期阶段。含铁血黄素性或动脉瘤样皮肤纤维瘤的临床鉴别诊断必须包括黑色素瘤和其他黑素细胞肿瘤、血管肿瘤、附属器肿瘤和非特异性囊肿。皮肤镜检查可提高色素沉着和非色素沉着性皮肤病变的诊断准确性。

目的

评估特定的皮肤镜标准。

方法

对6例含铁血黄素性或动脉瘤样皮肤纤维瘤患者进行皮肤镜检查(使用美国加利福尼亚州达纳角3Gen有限责任公司的DermLite Foto),以评估特定的皮肤镜标准。

结果

6个病变中的5个观察到一种多成分模式,其特征为中央有蓝色或红色均匀区域,伴有白色结构和周边精细的色素网以及血管结构。

结论

这种皮肤镜模式在大多数情况下可诊断含铁血黄素性或动脉瘤样皮肤纤维瘤。然而,这种多成分模式可能在某些黑色素瘤中出现,虽然它有助于确定动脉瘤样皮肤纤维瘤的临床诊断,但它可能并非该实体所特有。

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