Eisner Alexandra, Fagan Elizabeth J, Feierl Gebhard, Kessler Harald H, Marth Egon, Livermore David M, Woodford Neil
Institute of Hygiene, Medical University of Graz, Universitätsplatz 4, A-8010 Graz, Austria.
Antimicrob Agents Chemother. 2006 Feb;50(2):785-7. doi: 10.1128/AAC.50.2.785-787.2006.
Among 149 extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae isolates collected from patients in southeast Austria from 1998 to 2004, 38 Escherichia coli isolates and 11 Klebsiella spp. were CTX-M producers. The proportion of CTX-M-producers among all ESBL producers rose from 0% in 1998 to 58% in 2004. In general, CTX-M-producers had heterogeneous pulsed-field gel electrophoresis patterns, but one E. coli isolate was identical to a United Kingdom epidemic CTX-M-15-producing strain, although no epidemiological link with the United Kingdom was apparent.
在1998年至2004年从奥地利东南部患者中收集的149株产超广谱β-内酰胺酶(ESBL)的肠杆菌科细菌分离株中,38株大肠杆菌分离株和11株克雷伯菌属细菌为CTX-M生产者。CTX-M生产者在所有ESBL生产者中的比例从1998年的0%升至2004年的58%。总体而言,CTX-M生产者具有异质性脉冲场凝胶电泳图谱,但有一株大肠杆菌分离株与一株来自英国的流行产CTX-M-15菌株相同,尽管与英国没有明显的流行病学联系。