Khalil Samia N, Hanna Ehab, Farag Adel, Govindaraj Ranganathan, Vije Hadassah, Kee Spencer, Chuang Alice Z
University of Texas Medical School at Houston, USA.
Middle East J Anaesthesiol. 2005 Jun;18(2):391-400.
Our aim was to determine if the anesthesia technique for pain relief in children affects the stress response after minor surgery. A rise in blood glucose reflects stress-related effects in children who do not receive glucose perioperatively.
Twenty-eight children, ages 17-81 mos, undergoing elective urologic procedures, were enrolled. For pain relief, patients received presurgical caudal block (group 1), intravenous narcotics (group 2), or postsurgical caudal block (group 3). Blood samples were analyzed for glucose concentrations immediately after induction of anesthesia at baseline, 15 min after surgical incision (second sample), and 30 min after end of surgery (third sample).
In group 1 there was no change in glucose concentration in the second or third samples compared to baseline, while in group 3 there were significant increases in those samples, and in group 2 there was a significant increase in the second sample compared to baseline. Children in group 1 required significantly fewer narcotics in the postanesthesia care unit (PACU), and those in group 2 had significantly longer PACU and hospital durations.
Presurgical caudal analgesia attenuates the stress response of anesthesia and surgery and decreases postoperative narcotic use while narcotics prolong PACU and discharge times.
我们的目的是确定儿童疼痛缓解的麻醉技术是否会影响小手术后的应激反应。血糖升高反映了围手术期未接受葡萄糖的儿童的应激相关影响。
纳入28名年龄在17 - 81个月的接受择期泌尿外科手术的儿童。为缓解疼痛,患者接受术前骶管阻滞(第1组)、静脉注射麻醉剂(第2组)或术后骶管阻滞(第3组)。在麻醉诱导后即刻(基线)、手术切口后15分钟(第二个样本)和手术结束后30分钟(第三个样本)采集血样分析葡萄糖浓度。
与基线相比,第1组第二个和第三个样本中的葡萄糖浓度没有变化,而第3组这些样本中的葡萄糖浓度显著升高,第2组第二个样本与基线相比显著升高。第1组儿童在麻醉后护理单元(PACU)所需的麻醉剂明显较少,第2组儿童在PACU的时间和住院时间明显更长。
术前骶管镇痛可减轻麻醉和手术的应激反应,并减少术后麻醉剂的使用,而麻醉剂会延长PACU时间和出院时间。