两种市售脂肪酸补充剂（EfaVet和DVM Derm Caps）、月见草油和冷水鱼油对犬过敏性瘙痒治疗效果的比较：一项双盲研究

Comparison of the clinical efficacy of two commercial fatty acid supplements (EfaVet and DVM Derm Caps), evening primrose oil, and cold water marine fish oil in the management of allergic pruritus in dogs: a double-blinded study.

作者信息

Scott D W, Miller W H, Decker G A, Wellington J R

机构信息

Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York 14853.

出版信息

Cornell Vet. 1992 Jul;82(3):319-29.

PMID:1643883

Abstract

Twenty dogs with atopy or idiopathic pruritus were treated in a double-blinded clinical trial with computer-randomized and computer-generated sequences of 4 fatty acid-containing products: evening primrose oil, cold water marine fish oil, DVM Derm Caps, and EfaVet. Each dog received each product for a 2-week period. Five of 20 dogs (25%) had a good-to-excellent reduction in their level of pruritus with at least 1 of the products: evening primrose oil (2 dogs), DVM Derm Caps (1), EfaVet (1), DVM Derm Caps and cold water marine fish oil (1). Only 1 dog experienced a side effect (loose stools). Clinical response to fatty acid supplements appeared to be quite individualized, and independent of age, breed, sex, weight, duration of disease, specific diagnosis, or number of positive intradermal test reactions.

摘要

在一项双盲临床试验中，对20只患有特应性皮炎或特发性瘙痒症的犬进行了治疗，使用计算机随机生成的4种含脂肪酸产品序列：月见草油、冷水鱼油、DVM Derm Caps和EfaVet。每只犬使用每种产品2周。20只犬中有5只（25%）使用至少一种产品后瘙痒程度有良好至极佳的减轻：月见草油（2只犬）、DVM Derm Caps（1只）、EfaVet（1只）、DVM Derm Caps和冷水鱼油（1只）。只有1只犬出现了副作用（腹泻）。脂肪酸补充剂的临床反应似乎非常个体化，且与年龄、品种、性别、体重、疾病持续时间、具体诊断或皮内试验阳性反应数量无关。