含ω-3/ω-6脂肪酸的商业羊肉和大米日粮对特应性犬瘙痒的影响：一项单盲研究的结果。
Effect of an omega-3/omega-6 fatty acid-containing commercial lamb and rice diet on pruritus in atopic dogs: results of a single-blinded study.
作者信息
Scott D W, Miller W H, Reinhart G A, Mohammed H O, Bagladi M S
机构信息
Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York 14853, USA.
出版信息
Can J Vet Res. 1997 Apr;61(2):145-53.
Abstract
A commercial, lamb and rice, dog food with an omega-6:omega-3 fatty acid ratio of 5.5:1 was fed in a single-blinded, self-controlled clinical trial to 18 atopic dogs. The pruritus in 8 of these dogs (44.4%) was satisfactorily controlled within 7 to 21 d, returned within 3 to 14 d after the diet was withdrawn, and was again controlled when the diet was reinstated. Plasma and skin levels of examined fatty acids changed in all 18 dogs when their diet was switched to the test diet. Dogs responding to the test diet had a different pattern of fatty acid change as compared to the dogs which failed to respond to the diet, suggesting that there are subsets of atopic dogs with different fatty acid metabolism capabilities.
摘要
在一项单盲、自身对照临床试验中，给18只特应性犬喂食一种欧米伽6与欧米伽3脂肪酸比例为5.5:1的市售羊肉和大米狗粮。其中8只犬（44.4%）的瘙痒在7至21天内得到满意控制，停喂该日粮后3至14天复发，重新喂食后瘙痒再次得到控制。当所有18只犬的日粮换为试验日粮时，所检测脂肪酸的血浆和皮肤水平均发生了变化。与未对日粮产生反应的犬相比，对试验日粮有反应的犬的脂肪酸变化模式不同，这表明特应性犬存在具有不同脂肪酸代谢能力的亚组。
相似文献
1
2
Efficacy of an essential fatty acid-enriched diet in managing canine atopic dermatitis: a randomized, single-blinded, cross-over study.富含必需脂肪酸的饮食对犬特应性皮炎的疗效：一项随机、单盲、交叉研究。
Vet Dermatol. 2008 Jun;19(3):156-62. doi: 10.1111/j.1365-3164.2008.00670.x.
3
Multicenter veterinary practice assessment of the effects of omega-3 fatty acids on osteoarthritis in dogs.多中心兽医实践评估ω-3脂肪酸对犬骨关节炎的影响。
J Am Vet Med Assoc. 2010 Jan 1;236(1):59-66. doi: 10.2460/javma.236.1.59.
4
Essential fatty acids supplementation in different-stage atopic dogs fed on a controlled diet.在食用对照饮食的不同阶段特应性犬中补充必需脂肪酸。
J Anim Physiol Anim Nutr (Berl). 2005 Apr-Jun;89(3-6):203-7. doi: 10.1111/j.1439-0396.2005.00541.x.
5
The efficacy of commercially available veterinary diets recommended for dogs with atopic dermatitis.推荐用于特应性皮炎犬的市售兽医饮食的疗效。
Vet Dermatol. 2008 Oct;19(5):280-7. doi: 10.1111/j.1365-3164.2008.00688.x. Epub 2008 Aug 7.
6
Evaluation of the effects of omega-3 fatty acid-containing diets on the inflammatory stage of wound healing in dogs.含ω-3脂肪酸饮食对犬伤口愈合炎症阶段影响的评估。
Am J Vet Res. 1998 Jul;59(7):859-63.
7
Deficiency of n-6 polyunsaturated fatty acids is mainly responsible for atopic dermatitis-like pruritic skin inflammation in special diet-fed hairless mice.n-6 多不饱和脂肪酸缺乏主要导致特定饮食喂养无毛小鼠出现特应性皮炎样瘙痒性皮肤炎症。
Exp Dermatol. 2013 Apr;22(4):272-7. doi: 10.1111/exd.12120.
8
Evaluation of the effects of dietary supplementation with fish oil omega-3 fatty acids on weight bearing in dogs with osteoarthritis.评估补充鱼油ω-3脂肪酸饮食对骨关节炎犬负重的影响。
J Am Vet Med Assoc. 2010 Jan 1;236(1):67-73. doi: 10.2460/javma.236.1.67.
9
Randomized, double-blind, placebo-controlled clinical trial measuring the effect of a dietetic food on dermatologic scoring and pruritus in dogs with atopic dermatitis.一项随机、双盲、安慰剂对照的临床试验，旨在测量一种饮食食品对特应性皮炎犬的皮肤病评分和瘙痒的影响。
BMC Vet Res. 2021 Nov 19;17(1):354. doi: 10.1186/s12917-021-03063-w.
10
Plasma and skin concentrations of polyunsaturated fatty acids before and after supplementation with n-3 fatty acids in dogs with atopic dermatitis.特应性皮炎犬补充n-3脂肪酸前后多不饱和脂肪酸的血浆和皮肤浓度
Am J Vet Res. 2005 May;66(5):868-73. doi: 10.2460/ajvr.2005.66.868.
引用本文的文献
1
The Effect of Ethyl Esters of Linseed Oil on the Changes in the Fatty Acid Profile of Hair Coat Sebum, Blood Serum and Erythrocyte Membranes in Healthy Dogs.亚麻籽油乙酯对健康犬被毛皮脂、血清及红细胞膜脂肪酸谱变化的影响
Animals (Basel). 2023 Jul 9;13(14):2250. doi: 10.3390/ani13142250.
2
Nutrient profile, amino acid digestibility, true metabolizable energy, and indispensable amino acid scoring of whole hemp seeds for use in canine and feline diets.用于犬猫日粮的整粒大麻籽的营养概况、氨基酸消化率、真代谢能和必需氨基酸评分。
J Anim Sci. 2023 Jan 3;101. doi: 10.1093/jas/skad106.
3
NUTRITION AND HEALTH: COMPANION ANIMAL APPLICATIONS: Functional nutrition in livestock and companion animals to modulate the immune response.营养与健康：伴侣动物应用篇：调节免疫反应的功能性营养在畜牧和伴侣动物中的应用。
J Anim Sci. 2020 Mar 1;98(3). doi: 10.1093/jas/skaa035.
4
Erythrocyte and plasma fatty acid patterns in dogs with atopic dermatitis and healthy dogs in the same household.患有特应性皮炎的犬与同一家户中的健康犬的红细胞和血浆脂肪酸模式。
Can J Vet Res. 2006 Jul;70(3):191-6.
5
6
The fatty acid profile of subcutaneous fat and blood plasma in pruritic dogs and dogs without skin problems.患有瘙痒症的犬类和无皮肤问题的犬类皮下脂肪及血浆中的脂肪酸谱。
Can J Vet Res. 1998 Oct;62(4):275-8.
本文引用的文献
1
Nonsteroidal anti-inflammatory agents in the management of canine allergic pruritus.非甾体抗炎药在犬过敏性瘙痒症治疗中的应用
J S Afr Vet Assoc. 1993 Mar;64(1):52-6.
2
Diagnosis of food allergy in dogs.犬类食物过敏的诊断
J Am Vet Med Assoc. 1993 Jul 15;203(2):259-62.
3
Combined treatment with concentrated essential fatty acids and prednisolone in the management of canine atopy.浓缩必需脂肪酸与泼尼松龙联合治疗犬特应性皮炎
Vet Rec. 1994 Jan 8;134(2):30-2. doi: 10.1136/vr.134.2.30.
4
Atopic dermatitis in Norwegian dogs.挪威犬的特应性皮炎
Nord Vet Med. 1985 Mar-Apr;37(2):97-106.
5
Food hypersensitivity in 30 dogs.30只犬的食物过敏
J Am Vet Med Assoc. 1986 Apr 1;188(7):695-8.
6
Aspects of the immunopathogenesis of flea allergy dermatitis in dogs.犬蚤过敏性皮炎的免疫发病机制方面
Vet Immunol Immunopathol. 1987 Dec;17(1-4):483-94. doi: 10.1016/0165-2427(87)90164-4.
7
Discrimination in the provision of health care in relation to persons with infection with the human immunodeficiency virus.在提供医疗保健方面针对感染人类免疫缺陷病毒者的歧视。
Med J Aust. 1990 Feb 19;152(4):220. doi: 10.5694/j.1326-5377.1990.tb125164.x.
8
9
Comparison of the clinical efficacy of two commercial fatty acid supplements (EfaVet and DVM Derm Caps), evening primrose oil, and cold water marine fish oil in the management of allergic pruritus in dogs: a double-blinded study.两种市售脂肪酸补充剂（EfaVet和DVM Derm Caps）、月见草油和冷水鱼油对犬过敏性瘙痒治疗效果的比较：一项双盲研究
Cornell Vet. 1992 Jul;82(3):319-29.
10
Double blind, placebo-controlled, crossover study of evening primrose oil in the treatment of canine atopy.月见草油治疗犬特应性皮炎的双盲、安慰剂对照、交叉研究。
Vet Rec. 1992 Aug 1;131(5):97-9. doi: 10.1136/vr.131.5.97.
Zotero 插件