Symington L, Thakore S
Accident and Emergency Department, Ninewells Hospital, Dundee DD1 9SY, UK.
Emerg Med J. 2006 Feb;23(2):89-93. doi: 10.1136/emj.2005.023713.
Sedation for short but potentially painful procedures is often undertaken in the emergency department. The ideal sedative regimen should provide analgesia and anxiolysis with minimal side effects and cardiorespiratory depression and rapid recovery post-procedure. Propofol has found increasing popularity with anaesthetists for sedation in the operating theatre. This is a review of the current literature looking at the use of propofol for procedural sedation in the emergency department. A comprehensive literature search of Medline from 1966 to week 4 of 2005, Embase from 1980 to week 10 of 2005, and the Cochrane Library was carried out using the OVID interface. Eight articles were selected for review. The evidence suggests that propofol is both effective and safe to use in the emergency department. However, several of the papers reviewed used deep levels of sedation that are not recommended in the UK by non-anaesthetists.
在急诊科，对于短暂但可能引起疼痛的操作，常需进行镇静处理。理想的镇静方案应能提供镇痛和抗焦虑作用，副作用、心肺抑制最小，且操作后恢复迅速。丙泊酚在手术室麻醉中越来越受麻醉医生欢迎。本文是对当前文献的综述，探讨丙泊酚在急诊科用于操作镇静的情况。使用OVID界面，对1966年至2005年第4周的Medline、1980年至2005年第10周的Embase以及Cochrane图书馆进行了全面的文献检索。选取了8篇文章进行综述。证据表明，丙泊酚在急诊科使用既有效又安全。然而，所综述的几篇论文使用了深度镇静，这在英国非麻醉医生不推荐使用。
