Chlabicz Sławomir, Flisiak Robert, Grzeszczuk Anna, Kovalchuk Oksana, Prokopowicz Danuta, Chyczewski Lech
Department of Family Medicine and Community Nursing, Mieszka I 4 B, 15-054 Białystok, Poland.
World J Gastroenterol. 2006 Jan 7;12(1):141-5. doi: 10.3748/wjg.v12.i1.141.
To describe the risk profile of patients in hospital with hepatitis C virus (HCV) infection in Poland.
Using a structured questionnaire, all patients with confirmed HCV infection were interviewed about the risk factors.
Among the 250 patients studied, transfusion before 1993 was the primary risk factor in 26%, intravenous drug use setting in 9% and occupational exposure in health-care in 9%. Women were more likely to have a history of occupational exposure or transfusion before 1993 and less likely to undergo minor surgery. Known nosocomial risk factors (transfusion before 1993, dialysis) were responsible for 27% of infections, probable nosocomial factors (transfusions after 1992, minor surgery) for 14% and further 9% were occupationally acquired infections.
A careful history investigation can identify a known or probable risk factor for HCV acquisition in 59% of patients with HCV infection. Preventive activities in Poland should focus on infection control measures in health-care setting.
描述波兰住院丙型肝炎病毒（HCV）感染患者的风险特征。
采用结构化问卷，对所有确诊为HCV感染的患者进行危险因素访谈。
在研究的250例患者中，1993年前输血是26%患者的主要危险因素，静脉吸毒占9%，医疗保健行业职业暴露占9%。女性在1993年前更有可能有职业暴露或输血史，而接受小手术的可能性较小。已知的医院感染危险因素（1993年前输血、透析）导致27%的感染，可能的医院感染因素（1992年后输血、小手术）导致14%的感染，另有9%为职业获得性感染。
通过仔细的病史调查，59%的HCV感染患者可识别出已知或可能的HCV感染危险因素。波兰的预防措施应侧重于医疗保健机构的感染控制措施。
