Kim Tae-Hun, Joo Jong-Eun
Department of Internal Medicine and Medical Research Institute, Ewha Womans University Hospital, 911-1 Mok-Dong, Yangchun-Gu, Seoul 158-710, Mokdong South Korea.
World J Gastroenterol. 2006 Jan 7;12(1):150-3. doi: 10.3748/wjg.v12.i1.150.
A 39-year-old male patient complaining of bilateral hand joint arthralgia was evaluated and found to have chronic hepatitis C and systemic sarcoidosis involving lung, skin, liver, and spleen. Hepatic and cutaneous sarcoidoses were confirmed by the presence of numerous noncaseating granulomas on histological examination. Pulmonary and splenic involvements were diagnosed by imaging studies. Fifteen months later, the sarcoidotic lesions in lung, liver, and spleen were resolved by radiological studies and a liver biopsy showed no granuloma but moderate to severe inflammatory activity. systemic sarcoidosis is a rare comorbidity of chronic hepatitis C which may spontaneously resolve.
一名39岁男性患者因双侧手部关节疼痛前来就诊，经评估发现患有慢性丙型肝炎和累及肺、皮肤、肝脏及脾脏的系统性结节病。组织学检查发现大量非干酪样肉芽肿，从而确诊肝脏和皮肤结节病。通过影像学检查诊断出肺部和脾脏受累。15个月后，影像学检查显示肺、肝和脾的结节病病变已消退，肝脏活检未发现肉芽肿，但有中度至重度炎症活动。系统性结节病是慢性丙型肝炎的一种罕见合并症，可能会自发缓解。
