来自四膜虫的一类新型核仁RNA。
A novel class of nucleolar RNAs from Tetrahymena.
作者信息
Nielsen H, Orum H, Engberg J
机构信息
Department of Biochemistry B, Panum Institute, University of Copenhagen, Denmark.
出版信息
FEBS Lett. 1992 Aug 3;307(3):337-42. doi: 10.1016/0014-5793(92)80708-o.
We describe a family of at least four nucleolar RNAs (snoRNAs) from the ciliate, Tetrahymena. The snoRNAs are 120-140 nucleotides long, moderately AU-rich and contain no modified nucleotides. Their 5' ends are blocked by a cap of unknown nature. The snoRNAs can be folded into similar secondary structures consisting of two hairpins separated by a single-stranded AU-rich spacer. The sequences and secondary structures show no extensive sequence or secondary structure resemblance to any other small RNAs in the public databases.
我们描述了来自纤毛虫四膜虫的一个至少包含四种核仁RNA（snoRNA）的家族。这些snoRNA长度为120 - 140个核苷酸，富含AU且不含修饰核苷酸。它们的5'端被一种性质未知的帽结构封闭。这些snoRNA可以折叠成相似的二级结构，由两个发夹结构组成，中间隔着一个富含AU的单链间隔区。其序列和二级结构与公共数据库中任何其他小RNA均无广泛的序列或二级结构相似性。
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