Bachellerie J P, Michot B, Nicoloso M, Balakin A, Ni J, Fournier M J
Centre National de la Recherche Scientifique, Laboratoire de Biologie Moléculaire Eucaryote, Toulouse, France.
Trends Biochem Sci. 1995 Jul;20(7):261-4. doi: 10.1016/s0968-0004(00)89039-8.
A growing subset of small nucleolar RNAs (snoRNAs) contains long stretches of sequence complementarity to conserved sequences in mature ribosomal RNA (rRNA). This article reviews current knowledge about these complementarities and proposes that these antisense snoRNAs might function in pre-rRNA folding, base modification and ribosomal ribonucleoprotein assembly, in some cases acting as RNA chaperones.
一小部分不断增加的小核仁RNA（snoRNA）含有与成熟核糖体RNA（rRNA）中的保守序列具有长片段序列互补性的区域。本文综述了关于这些互补性的现有知识，并提出这些反义snoRNA可能在核糖体RNA前体折叠、碱基修饰和核糖体核糖核蛋白组装过程中发挥作用，在某些情况下还可充当RNA伴侣。
