Lovitt Steven, Moore Sandra L, Marden Franklin A
Department of Neurology, Baylor College of Medicine, University of Texas Health Science Center at Houston, TX 77030, USA.
Clin Neurophysiol. 2006 Mar;117(3):486-95. doi: 10.1016/j.clinph.2005.10.010. Epub 2006 Jan 27.
MRI has revolutionized the practice of many branches of medicine. However, within the field of Neurology MRI is used almost exclusively to examine the structure of portions of the central nervous system. Despite a limited number of objective tests, MRI remains an underutilized tool in the examination of the peripheral nervous system. This review will briefly discuss the limitations of current testing, and then summarize how the physics of MRI helps predict normal and abnormal findings in disease affecting skeletal muscle. The cardinal radiologic abnormalities affecting muscle (atrophy, hypertrophy, pseudohypertrophy, mass, and altered signal intensity) are reviewed. Special attention is given to how MRI can be utilized during the evaluation of such disorders. Finally, the roles of MRI as a prognostic tool and as a potential endpoint in long-term management of myopathy are evaluated.
磁共振成像（MRI）已经彻底改变了许多医学分支的实践。然而，在神经病学领域，MRI几乎仅用于检查中枢神经系统各部分的结构。尽管客观测试数量有限，但MRI在周围神经系统检查中仍是一种未得到充分利用的工具。本综述将简要讨论当前检测方法的局限性，然后总结MRI物理学如何有助于预测影响骨骼肌疾病的正常和异常表现。文中回顾了影响肌肉的主要放射学异常（萎缩、肥大、假性肥大、肿块和信号强度改变）。特别关注了在评估此类疾病时如何利用MRI。最后，评估了MRI作为预后工具以及在肌病长期管理中作为潜在终点的作用。
