University of California, Davis.
Keck School of Medicine, University of Southern California (USC), Los Angles, CA, USA.
Clin Imaging. 2021 Aug;76:38-41. doi: 10.1016/j.clinimag.2021.01.023. Epub 2021 Jan 28.
Imaging tools are potentially able to provide valuable data regarding the development of an efficient vaccine against viral diseases. Tracking immune cells in vivo by imaging modalities can help us understand the intrinsic behaviors of immune cells in response to vaccine components. Imaging patterns at the vaccination site and draining lymph nodes might provide useful information about the vaccine potency. Besides, serial lung CT imaging has been purposed to evaluate vaccine efficiency regarding its protection against typical lung lesions of viral pneumonias. On the other hand, vaccination causes various confusing radiologic patterns that pose diagnostic challenges for clinicians and pitfalls for reading radiologists. This manuscript reviews potential applications of imaging modalities in the process of vaccine development and also goes over some of the imaging findings/pitfalls following vaccination.
成像工具有可能为开发针对病毒性疾病的有效疫苗提供有价值的数据。通过成像方式追踪体内免疫细胞可以帮助我们了解免疫细胞对疫苗成分的内在反应。在接种部位和引流淋巴结处的成像模式可能为疫苗效力提供有用的信息。此外，连续的肺部 CT 成像已被提议用于评估疫苗对病毒性肺炎典型肺部病变的保护效率。另一方面，疫苗接种会引起各种混淆的放射学模式，给临床医生的诊断带来挑战，也给放射科医生的阅读带来陷阱。本文综述了成像方式在疫苗开发过程中的潜在应用，并回顾了接种疫苗后的一些成像发现/陷阱。
