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[巴西一家综合医院计算机断层扫描(胸部和腹部)肾上腺偶发瘤的患病率]

[Prevalence of adrenal incidentaloma at computed tomography (chest and abdominal) in a general hospital in Brazil].

作者信息

Ferreira Eleci V, Czepielewski Mauro A, Faccin Carlos Sasso, Accordi Melissa Coral, Furtado Alvaro Porto Alegre

机构信息

Serviço de Radiologia, Hospital de Clínicas de Porto Alegre, Faculdade de Medicina, UFRGS, Porto Alegre, RS.

出版信息

Arq Bras Endocrinol Metabol. 2005 Oct;49(5):769-75. doi: 10.1590/s0004-27302005000500017. Epub 2006 Jan 23.

Abstract

OBJECTIVE

To prospectively determine the prevalence of incidental adrenal lesions at computed tomography (CT) at an University Hospital in Brazil.

PATIENTS AND METHOD

A cross-sectional prospective study was performed to evaluate 3,382 consecutive patients with no known adrenal disease or malignancies who underwent chest and abdominal CT scans over a ten-month period. The cases of adrenal incidentaloma were defined by the presence of any change in gland contour, size or density. Kappa values were calculated, evaluating the intra and inter-observer agreement.

RESULTS

One hundred and one incidental adrenal masses were identified, corresponding to 83 cases and a prevalence of 2.5% (CI 95%: 1.0%-3.2%). Male patients presented a higher prevalence of incidentaloma than female (3.3% vs. 1.5%; p= 0.01). There was a significant association between older age and higher frequency of incidentaloma. Kappa of 0.76 and 0.83 (good and excellent agreement, respectively), were obtained in evaluating the intra and inter-observer agreements.

CONCLUSIONS

The prevalence of adrenal incidentaloma detected by CT was similar to that of various published retrospective clinical series. The two factors that independently influenced the distribution of incidentalomas were older age and being male.

摘要

目的

前瞻性确定巴西一家大学医院计算机断层扫描(CT)检查时肾上腺意外瘤的患病率。

患者与方法

开展一项横断面前瞻性研究,以评估在十个月期间连续接受胸部和腹部CT扫描的3382例无已知肾上腺疾病或恶性肿瘤的患者。肾上腺意外瘤病例通过腺体轮廓、大小或密度的任何变化来定义。计算kappa值,评估观察者内和观察者间的一致性。

结果

共识别出101个肾上腺意外肿块,对应83例患者,患病率为2.5%(95%置信区间:1.0%-3.2%)。男性患者意外瘤的患病率高于女性(3.3%对1.5%;p=0.01)。年龄较大与意外瘤的较高发生率之间存在显著关联。在评估观察者内和观察者间一致性时,kappa值分别为0.76和0.83(分别为良好和优秀一致性)。

结论

CT检测到的肾上腺意外瘤患病率与各种已发表的回顾性临床系列研究相似。独立影响意外瘤分布的两个因素是年龄较大和男性。

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