Anthony Shelagh, Leiper James, Vallance Patrick
Centre for Clinical Pharmacology, The British Heart Foundation Laboratories, University College London, UK.
Vasc Med. 2005 Jul;10 Suppl 1:S3-9. doi: 10.1191/1358863x05vm595oa.
Numerous reports have indicated that the plasma concentration of endogenously produced inhibitors of nitric oxide synthase are elevated in human disease states. In this review we discuss recent advances in our understanding of the enzymes responsible for the synthesis of these inhibitors.
大量报告表明,在人类疾病状态下,内源性一氧化氮合酶抑制剂的血浆浓度会升高。在这篇综述中,我们讨论了在理解负责合成这些抑制剂的酶方面的最新进展。