Graziotti Pierpaolo, Giusti Guido, Seveso Mauro, Taverna Gianluigi, Benetti Alessio, Maugeri Orazio, Pasini Luisa, Zandegiacomo Silvia, Piccinelli Alessandro, Maffezzini Massimo
Department of Urology, Istituto Clinico Humanitas, Rozzano, Italy.
Arch Ital Urol Androl. 2005 Dec;77(4):181-4.
To verify if nerve and seminal sparing radical prostatectomy could represent surgical solution for iatrogenic bladder neck prostatic urethra contracture without external sphincter involvement.
At our institution 4 patients have been submitted to nerve and seminal sparing radical prostatectomy for recurrent bladder neck-prostatic urethra contracture following TURP for middle size adenoma. In all cases bladder neck was reconstructed and a 20F silicon catheter was left in place for two weeks to stint the vesico-urethral anastomosis.
In all cases no significant perioperative complications were experienced. A normal voiding urethrogram preceded removal of the catheter 14 days postoperatively. Urinary continence was recovered by all of the patients. Uroflowmetry was persistently normal at periodic controls. With a mean follow-up of 36.3 months, no patient complained of symptomatic recurrence of urinary obstruction. In three previously potent patients, sexual activity with satisfactory intercourse was maintained.
Even though our experience is very limited in terms of number of patients and length of follow-up, we think that nerve and seminal sparing radical prostatectomy, because of the limited risk of major complications and the good result in terms of preservation of both urinary continence and erectile function, can be a reasonable solution for iatrogenic bladder neck-prostatic contracture after prostatic surgery for BPH.
验证保留神经和精囊的根治性前列腺切除术是否可作为治疗不涉及外括约肌的医源性膀胱颈前列腺尿道狭窄的手术方案。
在我们机构,4例因中等大小腺瘤行经尿道前列腺电切术(TURP)后复发性膀胱颈-前列腺尿道狭窄的患者接受了保留神经和精囊的根治性前列腺切除术。所有病例均重建了膀胱颈,并留置一根20F硅胶导管两周以支撑膀胱尿道吻合口。
所有病例均未出现明显的围手术期并发症。术后14天拔除导尿管前排尿尿道造影正常。所有患者均恢复了尿控。定期检查时尿流率持续正常。平均随访36.3个月,无患者主诉尿路梗阻症状复发。在3例术前有性功能的患者中,维持了满意性交的性活动。
尽管我们在患者数量和随访时间方面的经验非常有限,但我们认为,保留神经和精囊的根治性前列腺切除术,由于主要并发症风险有限,且在保留尿控和勃起功能方面效果良好,对于良性前列腺增生症前列腺手术后的医源性膀胱颈-前列腺狭窄可能是一种合理的解决方案。