Simonato Alchiede, Gregori Andrea, Lissiani Andrea, Carmignani Giorgio
"Luciano Giuliani" Department of Urology, University of Genoa, Genoa, Italy.
Eur Urol. 2007 Nov;52(5):1499-504. doi: 10.1016/j.eururo.2007.03.053. Epub 2007 Mar 26.
The treatment of posterior urethral strictures or bladder neck contracture associated with severe urinary incontinence after prostate surgery and failure of endoscopic treatments is controversial. We report our experience with a transperineal approach in two steps: end-to-end urethroplasty/anastomosis and subsequent artificial urinary sphincter implantation.
Between September 2001 and January 2005, we observed six patients (58-68 yr old), with a combination of severe urinary incontinence and posterior urethral stricture with anastomotic bladder neck contracture after prostate surgery. In all cases, repeated endoscopic treatments of the strictures failed. The patients underwent transperineal end-to-end urethroplasty or anastomosis followed by transperineal artificial urinary sphincter placement after 6 mo.
After the first surgical step, all patients were completely incontinent with absence of urethral strictures and complete anastomotic healing in all cases. Therefore, all patients underwent artificial urinary sphincter insertion. After a mean follow-up of 38 mo (range: 18-57 mo), five patients are continent with no postvoid residual urine and a perfectly functioning device. One artificial urinary sphincter was removed due to urethral erosion.
In patients with posterior urethral strictures or bladder neck contractures associated with severe urinary incontinence, an artificial urinary sphincter implantation as a second step allows verification of the outcome of a previous end-to-end urethroplasty or anastomosis and utilizes a dedicated operative field to reduce the risks of prosthesis implants.
前列腺手术后伴有严重尿失禁且内镜治疗失败的后尿道狭窄或膀胱颈挛缩的治疗存在争议。我们报告经会阴入路分两步进行治疗的经验:端端尿道成形术/吻合术以及随后的人工尿道括约肌植入术。
在2001年9月至2005年1月期间,我们观察了6例患者(年龄58 - 68岁),他们在前列腺手术后合并严重尿失禁以及后尿道狭窄并伴有吻合口膀胱颈挛缩。所有病例中,对狭窄的反复内镜治疗均失败。患者接受了经会阴端端尿道成形术或吻合术,6个月后再行经会阴人工尿道括约肌置入术。
在第一步手术后,所有患者均完全尿失禁,尿道狭窄消失且吻合口全部愈合。因此,所有患者均接受了人工尿道括约肌植入。平均随访38个月(范围:18 - 57个月)后,5例患者实现控尿,排尿后无残余尿且装置功能良好。1例人工尿道括约肌因尿道侵蚀而取出。
对于伴有严重尿失禁的后尿道狭窄或膀胱颈挛缩患者,第二步进行人工尿道括约肌植入可验证先前端端尿道成形术或吻合术的效果,并利用专门的手术区域降低假体植入的风险。