Ade W R, Hino T, Kaizuka H, Wada J
Juro Wada Commemorative Heart & Lung Institute, Yuden Clinic & Akasaka Hospital Medical Center, Tokyo, Japan.
Int Surg. 1992 Apr-Jun;77(2):108-10.
Recent statistics indicate that one serious event occurs once in every 300 perfusions. We have devised a cybernetic approach using photosensors and pressure sensors at critical points of the circuit which should allow feedback regulation of the bypass according to the changes in venous return. In order to avoid overtransfusion, left atrial pressure control is employed. This also enables automatic weaning and facilitates partial bypass. In the clinical setting a test system proved to be accommodated to prevent gross air contamination of the arterial line. Based on vast clinical experience with the conventional method of extrapulmonary circulation, the logical extension of this work will be the development of a compact pump oxygenator utilizing hemofilters, the pump portion of which can be temporarily implanted until the cardiac function has been restored. It is autoregulated and, if the need arises, controlled by the anesthetist, one of whose primary concerns will be physiological perfusion.
最近的统计数据表明，每300次灌注中就会发生一次严重事件。我们设计了一种控制论方法，在回路的关键点使用光电传感器和压力传感器，这应该能够根据静脉回流的变化对旁路进行反馈调节。为了避免输血过量，采用左心房压力控制。这也能够实现自动撤机并便于部分旁路。在临床环境中，一个测试系统被证明可以防止动脉管路受到严重空气污染。基于体外循环传统方法的大量临床经验，这项工作的合理延伸将是开发一种利用血液滤过器的紧凑型泵氧合器，其泵部分可以临时植入，直到心脏功能恢复。它是自动调节的，如果有需要，由麻醉师控制，麻醉师主要关注的问题之一将是生理灌注。
