风湿性疾病患者的喉部评估。
Laryngeal assessment in rheumatic disease patients.
作者信息
Ramos Hugo Valter Lisboa, Pillon Jackeline, Kosugi Eduardo M, Fujita Reginaldo, Pontes Paulo
机构信息
Department of Otorhinolaryngology and Head and Neck Surgery, UNIFESP-EPM.
出版信息
Braz J Otorhinolaryngol. 2005 Jul-Aug;71(4):499-503. doi: 10.1016/s1808-8694(15)31206-4. Epub 2005 Dec 15.
UNLABELLED
Rheumatic diseases usually promote several systemic disorders, which can affect blood vessels, mucosa and serosa of the aerodigestive tract. Scarce laryngeal involvement has been described in these patients and this study aims at investigating laryngeal alterations found in patients with rheumatic diseases.
STUDY DESIGN
Transversal cohort.
MATERIAL AND METHOD
A transversal study was developed with systemic lupus erythematous, systemic sclerosis and mixed connective tissue disease's patients. They were evaluated by means of clinical examinations and videolaryngoestroboscopy.
RESULTS
Twenty-seven patients were included in the study, 26 succeeded in completing the videolaryngoestroboscopy. Laryngeal abnormalities were seen in 11 of 12 patients with lupus, in all 11 patients with sclerodermia and in 3 patients with mixed connective tissue disease. Vocal fold bamboo node was observed in 5 patients and 92.3% of all patients presented laryngeal signs of gastroesophageal reflux disease.
CONCLUSION
We noticed 5 vocal fold bamboo nodes and gastroesophageal reflux disease in almost all patients.
未标注
风湿性疾病通常会引发多种全身性疾病，这些疾病可影响气道消化道的血管、黏膜和浆膜。在这些患者中，喉部受累情况较为罕见，本研究旨在调查风湿性疾病患者的喉部改变。
研究设计
横向队列研究。
材料与方法
对系统性红斑狼疮、系统性硬化症和混合性结缔组织病患者开展横向研究。通过临床检查和视频喉镜频闪检查对他们进行评估。
结果
27例患者纳入研究，26例成功完成视频喉镜频闪检查。12例狼疮患者中有11例出现喉部异常，11例硬皮病患者全部出现喉部异常，3例混合性结缔组织病患者中有3例出现喉部异常。5例患者观察到声带竹节样改变，所有患者中有92.3%出现胃食管反流病的喉部体征。
结论
我们注意到5例声带竹节样改变，且几乎所有患者都有胃食管反流病。
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