Hehenkamp Wouter J K, Volkers Nicole A, Birnie Erwin, Reekers Jim A, Ankum Willem M
Department of Gynaecology, Academic Medical Centre, Meibergdreef 9, Amsterdam, AZ, 1105, The Netherlands.
Cardiovasc Intervent Radiol. 2006 Mar-Apr;29(2):179-87. doi: 10.1007/s00270-005-0195-9.
To evaluate the safety and efficacy of uterine artery embolization (UAE) and hysterectomy for symptomatic uterine fibroids by means of a randomized controlled trial. The present paper analyses short-term outcomes, i.e., pain and return to daily activities.
Patients were randomized (1:1) to UAE or hysterectomy. Pain was assessed during admission and after discharge, both quantitatively and qualitatively, using a numerical rating scale and questionnaires. Time to return to daily activities was assessed by questionnaire.
Seventy-five patients underwent hysterectomy and 81 patients underwent UAE. UAE patients experienced significantly less pain during the first 24 hr after treatment (p = 0.012). Non-white patients had significantly higher pain scores. UAE patients returned significantly sooner to daily activities than hysterectomy patients (for paid work: 28.1 versus 63.4 days; p < 0.001). In conclusion, pain appears to be less after UAE during hospital stay. Return to several daily activities was in favor of UAE in comparison with hysterectomy.
通过一项随机对照试验评估子宫动脉栓塞术（UAE）和子宫切除术治疗有症状子宫肌瘤的安全性和有效性。本文分析短期结果，即疼痛和恢复日常活动情况。
患者按1:1随机分为接受UAE组或子宫切除组。使用数字评分量表和问卷对入院期间和出院后的疼痛进行定量和定性评估。通过问卷评估恢复日常活动的时间。
75例患者接受了子宫切除术，81例患者接受了UAE。UAE组患者在治疗后的前24小时疼痛明显较轻（p = 0.012）。非白人患者的疼痛评分明显更高。UAE组患者恢复日常活动的时间明显早于子宫切除组患者（从事有偿工作：28.1天对63.4天；p < 0.001）。总之，住院期间UAE术后疼痛似乎较轻。与子宫切除术相比，恢复多项日常活动方面UAE更具优势。
