Spiro S G, Charman J, Das I, Reid L
J Clin Pathol. 1975 Jan;28(1):60-5. doi: 10.1136/jcp.28.1.60.
In a case of bronchorrhoea associated with alveolar cell carcinoma thf rheological and chemical features of the sputum indicated that it was bronchial fluid and not saliva and part bronchial secretion, partly serum transudate. The viscosity and chemical constituents were similar to those found in bronchorrhoea when associated with chronic bronchitis, asthma, or bronchiectasis. The surfactant studies suggested an alveolar origin for most of thf fluid, while the failure of fluid restriction, corticosteroids, atropine, or cytotoxic drugs to influence the sputum volume and properties indicated that the cells responsible are "autonomous".
在一例与肺泡细胞癌相关的支气管溢液病例中,痰液的流变学和化学特征表明其为支气管分泌物而非唾液,且部分为支气管分泌物,部分为血清渗出液。其粘度和化学成分与慢性支气管炎、哮喘或支气管扩张相关的支气管溢液中的情况相似。表面活性剂研究表明大部分液体来源于肺泡,而限制液体摄入、使用皮质类固醇、阿托品或细胞毒性药物均未能影响痰液的量和性质,这表明产生痰液的细胞是“自主的”。