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海鱼分枝杆菌,一种与结节病相关的其他感染因子:多病因假说。

Mycobacterium marinum, a further infectious agent associated with sarcoidosis: the polyetiology hypothesis.

作者信息

Moling Oswald, Sechi Leonardo A, Zanetti Stefania, Seebacher Christine, Rossi Patrizia, Rimenti Giovanni, Pagani Leonardo, Vedovelli Claudio

机构信息

Division of Infectious Diseases, Ospedale Generale, Bolzano, Italy.

出版信息

Scand J Infect Dis. 2006;38(2):148-52. doi: 10.1080/00365540500277540.

Abstract

A 39-y-old male had a diagnosis of sarcoidosis and corticosteroid therapy was started. Surprisingly, following his discharge from hospital, Mycobacterium marinum was isolated in 1 of 3 sputum samples taken 7 weeks earlier on admission. After this, Mycobacterium marinum-DNA was identified in the stored lung biopsies by the PCR-RFLP of the hsp65 gene.

摘要

一名39岁男性被诊断为结节病,并开始接受皮质类固醇治疗。令人惊讶的是,他出院后,在入院7周前采集的3份痰液样本中的1份中分离出了海分枝杆菌。此后,通过hsp65基因的PCR-RFLP在储存的肺活检组织中鉴定出海分枝杆菌DNA。

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