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Buruli Ulcer, a Prototype for Ecosystem-Related Infection, Caused by Mycobacterium ulcerans.布鲁里溃疡,一种由溃疡分枝杆菌引起的与生态系统相关感染的原型。
Clin Microbiol Rev. 2017 Dec 13;31(1). doi: 10.1128/CMR.00045-17. Print 2018 Jan.
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On the origin of Mycobacterium ulcerans, the causative agent of Buruli ulcer.关于导致溃疡分枝杆菌病(Buruli 溃疡)的病原体,溃疡分枝杆菌的起源。
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Mycobacterium marinum, a further infectious agent associated with sarcoidosis: the polyetiology hypothesis.海鱼分枝杆菌,一种与结节病相关的其他感染因子:多病因假说。
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Pulmonary infection due to Mycobacterium marinum in an immunocompetent patient.免疫功能正常患者发生的海分枝杆菌肺部感染。
Clin Infect Dis. 2005 Jan 1;40(1):206-8. doi: 10.1086/426693.
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Buruli ulcer: a systemic disease.布氏杆菌溃疡:一种全身性疾病。
Clin Infect Dis. 2003 Sep 15;37(6):e78-82. doi: 10.1086/377170. Epub 2003 Aug 26.

免疫功能正常患者的肺部感染。

lung infection in an immunocompetent patient.

机构信息

American University of Beirut Medical Center, Beirut, Lebanon.

Infectious Diseases, American University of Beirut Medical Center, Beirut, Lebanon.

出版信息

BMJ Case Rep. 2022 Aug 9;15(8):e250547. doi: 10.1136/bcr-2022-250547.

DOI:10.1136/bcr-2022-250547
PMID:35944937
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9367185/
Abstract

has been implicated in cutaneous manifestations in humans, causing persistent wounds called Buruli ulcer. However, it has not been associated with pulmonary infections in humans to date. Herein, we report a case of an immunocompetent adult man with no underlying medical problems presenting with dyspnoea and generalised malaise and diagnosed with lung infection. The patient was prescribed clarithromycin 500 mg two times per day, rifampin 300 mg two tablets daily and moxifloxacin 400 mg daily for 6 months, with complete resolution of his symptoms.

摘要

已被牵连到人类的皮肤表现中,导致持续的伤口,称为布鲁里溃疡。然而,迄今为止,它尚未与人类的肺部感染有关。在此,我们报告了一例免疫功能正常的成年男性,无潜在的医疗问题,表现为呼吸困难和全身不适,并被诊断为肺部感染。患者被开了克拉霉素 500 毫克,每日两次;利福平 300 毫克,每日两片;莫西沙星 400 毫克,每日一次,共 6 个月,症状完全缓解。