Butland B K, Strachan D P, Crawley-Boevey E E, Anderson H R
Division of Community Health Sciences, St George's, University of London, Cranmer Terrace, London SW17 ORE, UK.
Thorax. 2006 May;61(5):383-7. doi: 10.1136/thx.2005.043646. Epub 2006 Jan 31.
Hospital admission rates for asthma in Britain rose during the 1980s and fell during the 1990s, but less is known about recent trends in the prevalence of asthma.
In 1991 and 2002 the same questionnaire was distributed to parents of all school pupils in year 3 (aged 7-8 years) in the London borough of Croydon. Parents of currently wheezy children were then invited for home interview (100% targeted in 1991, 66% in 2002).
The prevalence of wheeze during the previous year increased from 12.9% in 1991 to 17.8% in 2002 (prevalence ratio 1.39 (95% CI 1.23 to 1.56)). Increases were observed in frequent (1.54 (95% CI 1.16 to 2.03)) and infrequent attacks, severe speech limiting episodes (2.25 (95% CI 1.34 to 3.77)), and night waking (1.36 (95% CI 1.07 to 1.72)), and in the reported use of steroids (19.9% v 64.1% of currently wheezy children). Nevertheless, the proportions reporting a visit to the GP at his/her surgery for wheeze in the previous year (prevalence ratio 1.15 (95% CI 0.91 to 1.45)) or an outpatient visit (0.98 (95% CI 0.49 to 1.94)) changed little and an increase in reported casualty attendance (1.66 (95% CI 0.89 to 3.07)) was non-significant.
There is evidence of an increase in the prevalence of asthma among British primary school children between 1991 and 2002. The absence of a corresponding increase in health service utilisation data may reflect more widespread prophylactic treatment and/or changes in the use and provision of medical services.
20世纪80年代英国哮喘患者的住院率上升,90年代下降,但对于哮喘患病率的近期趋势了解较少。
1991年和2002年,向伦敦克罗伊登区所有三年级(7-8岁)学童的家长发放了相同的问卷。随后邀请目前有喘息症状儿童的家长进行家访(1991年目标回访率为100%,2002年为66%)。
前一年喘息的患病率从1991年的12.9%上升至2002年的17.8%(患病率比值1.39(95%可信区间1.23至1.56))。频繁发作(1.54(95%可信区间1.16至2.03))和不频繁发作、严重影响言语的发作次数(2.25(95%可信区间1.34至3.77))以及夜间醒来次数(1.36(95%可信区间1.07至1.72))均有所增加,报告使用类固醇药物的情况也有所增加(目前有喘息症状儿童中,这一比例从19.9%升至64.1%)。然而,报告前一年因喘息前往全科医生诊所就诊的比例(患病率比值1.15(95%可信区间0.91至1.45))或门诊就诊比例(0.98(95%可信区间0.49至1.94))变化不大,报告的急诊就诊增加情况(1.66(95%可信区间0.89至3.07))不显著。
有证据表明1991年至2002年间英国小学生哮喘患病率有所上升。卫生服务利用数据未相应增加可能反映了预防治疗更为广泛和/或医疗服务使用及提供情况的变化。