Sakai Joseph T, Mikulich-Gilbertson Susan K, Crowley Thomas J
Division of Substance Dependence, University of Colorado School of Medicine, Denver 80262, USA.
Am J Drug Alcohol Abuse. 2006;32(1):29-40. doi: 10.1080/00952990500328513.
Adolescent inhalant users are significantly more likely than other patients to have conduct disorder, to report abuse and neglect, and to have previously attempted suicide. Yet little has been published regarding treatment outcome for inhalant users.
Eighty male adolescents admitted to a residential treatment program underwent baseline assessment during treatment, and follow-up assessment at two-years post admission. Subjects reporting any lifetime inhalant use at baseline (n = 34) were compared to the other patients (n = 46) on 4 outcome variables.
Adolescents reporting any lifetime inhalant use at baseline assessment reported twice as many past-year conduct disorder symptoms at two-year follow up (p = 0.03). The relationship between inhalant use and conduct disorder symptoms remained significant (p = 0.03) in analyses that controlled for age, time in jail or restricted environments in the 6-months preceding follow-up, as well as baseline-reported lifetime number of conduct disorder symptoms. Inhalant users were not significantly worse on these other outcome measures: crime in the last month (p = 0.60), days of nontobacco substance use in the last 6 months (p = 0.65), or, commission of selected crimes in the last 6 months (p = 0.06).
Inhalant use among adolescent males in treatment for substance and behavior problems may predict more severe conduct disorder symptoms after treatment.
青少年吸入剂使用者比其他患者更有可能患有品行障碍、报告遭受虐待和忽视，并且曾尝试自杀。然而，关于吸入剂使用者的治疗结果，几乎没有相关文献发表。
80名入住住院治疗项目的男性青少年在治疗期间接受了基线评估，并在入院两年后进行了随访评估。将在基线时报告有任何终生吸入剂使用史的受试者（n = 34）与其他患者（n = 46）在4个结果变量上进行比较。
在基线评估时有任何终生吸入剂使用史的青少年在两年随访时报告的过去一年品行障碍症状数量是其他患者的两倍（p = 0.03）。在控制了年龄、随访前6个月在监狱或受限环境中的时间以及基线报告的终生品行障碍症状数量的分析中，吸入剂使用与品行障碍症状之间的关系仍然显著（p =
