Pichichero Michael E
University of Rochester Medical Center, 601 Elmwood Avenue, Rochester, NY 14642, USA.
J Fam Pract. 2006 Feb;55(2):106-12.
The widely quoted cross-allergy risk of 10% between penicillin and cephalosporins is a myth. Cephalothin, cephalexin, cefadroxil, and cefazolin confer an increased risk of allergic reaction among patients with penicillin allergy. Cefprozil, cefuroxime, cefpodoxime, ceftazidime, and ceftriaxone do not increase risk of an allergic reaction.
青霉素和头孢菌素之间广泛引用的10%交叉过敏风险是个误区。头孢噻吩、头孢氨苄、头孢羟氨苄和头孢唑林会增加青霉素过敏患者发生过敏反应的风险。头孢丙烯、头孢呋辛、头孢泊肟、头孢他啶和头孢曲松不会增加过敏反应风险。