Coscojuela P, Llauger J, Pérez C, Germá J, Castañer E
Department of Radiodiagnostics, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
Eur J Radiol. 1991 Mar-Apr;12(2):138-40. doi: 10.1016/0720-048x(91)90116-d.
Radiologic findings in four patients with metastatic mixed germ-cell tumors of the testis are presented. In all cases metastases had increased in size following chemotherapy in spite of normal biomarker levels, and histological study of the residual masses showed mature teratoma with an absence of malignant cells, thus confirming the diagnosis of growing teratoma syndrome. At present CT appears to be the best technique both for diagnosis and follow-up in these patients. In one case, the growing teratoma syndrome presented as cavitation of a pulmonary nodular lesion, a finding rarely described in the literature, and with CT demonstration not reported.
本文报告了4例睾丸转移性混合性生殖细胞肿瘤患者的放射学检查结果。在所有病例中，尽管生物标志物水平正常，但化疗后转移灶仍增大，对残留肿块的组织学研究显示为成熟畸胎瘤，无恶性细胞，从而确诊为生长性畸胎瘤综合征。目前，CT似乎是这些患者诊断和随访的最佳技术。在1例病例中，生长性畸胎瘤综合征表现为肺结节性病变空洞形成，这一发现文献中鲜有描述，且CT表现也未见报道。
