• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
The nodD gene of Rhizobium leguminosarum is autoregulatory and in the presence of plant exudate induces the nodA,B,C genes.根瘤菌 nodD 基因是自我调控的，在植物分泌物的存在下，诱导 nodA、B、C 基因的表达。
EMBO J. 1985 Dec 16;4(13A):3369-73. doi: 10.1002/j.1460-2075.1985.tb04092.x.
2
Root Exudates of Various Host Plants of Rhizobium leguminosarum Contain Different Sets of Inducers of Rhizobium Nodulation Genes.根瘤菌宿主植物的根分泌物包含不同的根瘤菌结瘤基因诱导物。
Plant Physiol. 1988 Apr;86(4):1298-303. doi: 10.1104/pp.86.4.1298.
3
Induction of Rhizobium meliloti nodC expression by plant exudate requires nodD.植物分泌物诱导苜蓿根瘤菌nodC表达需要nodD。
Proc Natl Acad Sci U S A. 1985 Oct;82(19):6609-13. doi: 10.1073/pnas.82.19.6609.
4
The Rhizobium leguminosarum nodulation gene nodF encodes a polypeptide similar to acyl-carrier protein and is regulated by nodD plus a factor in pea root exudate.根瘤菌属植物的结瘤基因 nodF 编码一种与酰基辅酶 A 相似的多肽，受 nodD 以及豌豆根分泌物中的一个因子调控。
EMBO J. 1986 Apr;5(4):647-52. doi: 10.1002/j.1460-2075.1986.tb04262.x.
5
Two inverted repeats in the nodD promoter region are involved in nodD regulation in Rhizobium leguminosarum.豆科根瘤菌中nodD启动子区域的两个反向重复序列参与nodD调控。
Gene. 1994 Jul 22;145(1):87-90. doi: 10.1016/0378-1119(94)90327-1.
6
Activation of the nodA promoter by the nodD genes of Rhizobium galegae induced by synthetic flavonoids or Galega orientalis root exudate.合成黄酮类化合物或东方山羊豆根分泌物诱导的山羊豆根瘤菌nodD基因对nodA启动子的激活作用。
FEMS Microbiol Lett. 2003 Feb 28;219(2):225-32. doi: 10.1016/S0378-1097(02)01206-5.
7
Host-specific regulation of nodulation genes in Rhizobium is mediated by a plant-signal, interacting with the nodD gene product.根瘤菌中结瘤基因的宿主特异性调节是由一种与 nodD 基因产物相互作用的植物信号介导的。
EMBO J. 1987 Apr;6(4):841-8. doi: 10.1002/j.1460-2075.1987.tb04829.x.
8
Regulatory functions of the three nodD genes of Rhizobium leguminosarum biovar phaseoli.菜豆根瘤菌生物变种三个nodD基因的调控功能
Mol Microbiol. 1990 Jun;4(6):933-41. doi: 10.1111/j.1365-2958.1990.tb00666.x.
9
Rhizobium nod Gene Inducers Exuded Naturally from Roots of Common Bean (Phaseolus vulgaris L.).根瘤菌结瘤基因诱导物从普通菜豆（Phaseolus vulgaris L.）的根部自然分泌。
Plant Physiol. 1991 Oct;97(2):759-64. doi: 10.1104/pp.97.2.759.
10
Analysis of the major inducers of the Rhizobium nodA promoter from Vicia sativa root exudate and their activity with different nodD genes.来自蚕豆根分泌物的根瘤菌nodA启动子的主要诱导物分析及其与不同nodD基因的活性。
Plant Mol Biol. 1989 Aug;13(2):175-88. doi: 10.1007/BF00016136.

引用本文的文献

1
Stabilisation of the RirA [4Fe-4S] cluster results in loss of iron-sensing function.RirA [4Fe-4S] 簇的稳定导致铁感应功能丧失。
Chem Sci. 2023 Aug 22;14(36):9744-9758. doi: 10.1039/d3sc03020b. eCollection 2023 Sep 20.
2
Adaptive Evolution of Rhizobial Symbiosis beyond Horizontal Gene Transfer: From Genome Innovation to Regulation Reconstruction.根瘤菌共生的适应性进化超越了水平基因转移：从基因组创新到调控重建。
Genes (Basel). 2023 Jan 20;14(2):274. doi: 10.3390/genes14020274.
3
RhizoBindingSites, a Database of DNA-Binding Motifs in Nitrogen-Fixing Bacteria Inferred Using a Footprint Discovery Approach.RhizoBindingSites，一个利用足迹发现方法推断出的固氮细菌中DNA结合基序的数据库。
Front Microbiol. 2020 Nov 5;11:567471. doi: 10.3389/fmicb.2020.567471. eCollection 2020.
4
Rhizobium leguminosarum bv. trifolii NodD2 Enhances Competitive Nodule Colonization in the Clover-Rhizobium Symbiosis.三叶草根瘤菌 NodD2 增强三叶草-根瘤菌共生体中的竞争结瘤定殖。
Appl Environ Microbiol. 2020 Sep 1;86(18). doi: 10.1128/AEM.01268-20.
5
Transcriptomic Studies of the Effect of nod Gene-Inducing Molecules in Rhizobia: Different Weapons, One Purpose.根瘤菌中结瘤基因诱导分子作用的转录组学研究：不同武器，同一目的。
Genes (Basel). 2017 Dec 21;9(1):1. doi: 10.3390/genes9010001.
6
Bacterial SBP56 identified as a Cu-dependent methanethiol oxidase widely distributed in the biosphere.鉴定出一种广泛分布于生物圈中的依赖 Cu 的甲硫醇氧化酶——细菌 SBP56。
ISME J. 2018 Jan;12(1):145-160. doi: 10.1038/ismej.2017.148. Epub 2017 Oct 24.
7
The Absence of the N-acyl-homoserine-lactone Autoinducer Synthase Genes and Increases the Copy Number of the Symbiotic Plasmid in NGR234.N-酰基高丝氨酸内酯自诱导物合成酶基因的缺失并增加了NGR234中共生质粒的拷贝数。
Front Microbiol. 2016 Nov 18;7:1858. doi: 10.3389/fmicb.2016.01858. eCollection 2016.
8
Identification of a core set of rhizobial infection genes using data from single cell-types.利用来自单一细胞类型的数据鉴定根瘤菌感染基因的核心集。
Front Plant Sci. 2015 Jul 28;6:575. doi: 10.3389/fpls.2015.00575. eCollection 2015.
9
Molecular basis of the establishment and functioning of a N2-fixing root nodule.固氮根瘤建立和运作的分子基础。
World J Microbiol Biotechnol. 1994 Nov;10(6):612-30. doi: 10.1007/BF00327946.
10
Control of the expression of bacterial genes involved in symbiotic nitrogen fixation.控制参与共生固氮的细菌基因的表达。
World J Microbiol Biotechnol. 1993 Jul;9(4):444-54. doi: 10.1007/BF00328032.

本文引用的文献

1
Cloning of the symbiotic region of Rhizobium leguminosarum: the nodulation genes are between the nitrogenase genes and a nifA-like gene.根瘤菌共生区的克隆：结瘤基因位于固氮酶基因和一个类似于 nifA 的基因之间。
EMBO J. 1983;2(6):947-52. doi: 10.1002/j.1460-2075.1983.tb01526.x.
2
The infection of clover root hairs by nodule bacteria studied by a simple glass slide technique.用一种简单的载玻片技术研究根瘤菌对三叶草根毛的感染。
J Gen Microbiol. 1957 Apr;16(2):374-81. doi: 10.1099/00221287-16-2-374.
3
Broad host range DNA cloning system for gram-negative bacteria: construction of a gene bank of Rhizobium meliloti.用于革兰氏阴性菌的广宿主范围DNA克隆系统：苜蓿根瘤菌基因文库的构建
Proc Natl Acad Sci U S A. 1980 Dec;77(12):7347-51. doi: 10.1073/pnas.77.12.7347.
4
Analysis of gene control signals by DNA fusion and cloning in Escherichia coli.通过在大肠杆菌中进行DNA融合和克隆分析基因控制信号。
J Mol Biol. 1980 Apr;138(2):179-207. doi: 10.1016/0022-2836(80)90283-1.
5
Cloning and analysis of strong promoters is made possible by the downstream placement of a RNA termination signal.通过在下游放置RNA终止信号，使得强启动子的克隆和分析成为可能。
Proc Natl Acad Sci U S A. 1981 Aug;78(8):4936-40. doi: 10.1073/pnas.78.8.4936.
6
DNA sequence of the Rhizobium leguminosarum nodulation genes nodAB and C required for root hair curling.豆科根瘤菌根毛卷曲所需的结瘤基因nodAB和C的DNA序列。
Nucleic Acids Res. 1984 Dec 21;12(24):9497-508. doi: 10.1093/nar/12.24.9497.
7
Nucleotide sequence of Rhizobium meliloti nodulation genes.苜蓿根瘤菌结瘤基因的核苷酸序列。
Nucleic Acids Res. 1984 Dec 21;12(24):9509-24. doi: 10.1093/nar/12.24.9509.
8
Specific-purpose plasmid cloning vectors. II. Broad host range, high copy number, RSF1010-derived vectors, and a host-vector system for gene cloning in Pseudomonas.专用质粒克隆载体。II. 广泛宿主范围、高拷贝数、源自RSF1010的载体以及用于假单胞菌基因克隆的宿主-载体系统。
Gene. 1981 Dec;16(1-3):237-47. doi: 10.1016/0378-1119(81)90080-9.
9
Mechanism of araC autoregulation and the domains of two overlapping promoters, Pc and PBAD, in the L-arabinose regulatory region of Escherichia coli.大肠杆菌L-阿拉伯糖调控区域中araC自动调节机制以及两个重叠启动子Pc和PBAD的结构域
Proc Natl Acad Sci U S A. 1981 Feb;78(2):752-6. doi: 10.1073/pnas.78.2.752.
10
A general method for site-directed mutagenesis in prokaryotes.一种原核生物中定点诱变的通用方法。
Nature. 1981 Jan 1;289(5793):85-8. doi: 10.1038/289085a0.

根瘤菌 nodD 基因是自我调控的，在植物分泌物的存在下，诱导 nodA、B、C 基因的表达。

The nodD gene of Rhizobium leguminosarum is autoregulatory and in the presence of plant exudate induces the nodA,B,C genes.

机构信息

John Innes Institute, Colney Lane, Norwich NR4 7UH, UK.

出版信息

EMBO J. 1985 Dec 16;4(13A):3369-73. doi: 10.1002/j.1460-2075.1985.tb04092.x.

DOI:10.1002/j.1460-2075.1985.tb04092.x
PMID:16453650
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC554672/
Abstract

To analyse nod gene expression in Rhizobium leguminosarum, a broad host-range lacZ protein fusion vector was constructed. Two protein fusions, nodC-lacZ and nodD-lacZ, were used to measure the regulation of expression of the promoters of the nodA,B,C and the nodD transcripts by measuring the induced levels of beta-galactosidase activity in R. leguminosarum. In the absence of plant root exudate the nodD-lacZ hybrid was expressed but the nodC-lacZ hybrid was not. The expression of the nodD-lacZ hybrid was repressed in R. leguminosarum strains containing an intact cloned nodD gene indicating that the nodD gene is autoregulatory. The induction of the nodC-lacZ hybrid required both the nodD gene and a component present in plant root exudate. Therefore the nodD gene acts both as a repressor and as an activator of gene expression. The nodD gene is adjacent to nodA and transcribed divergently from nodA,B,C with only approximately 300 nucleotides between the coding regions of nodA and nodD. Within this intergenic region is a unique BclI site and, using nodC-lacZ or nodD-lacZ translational fusions with this BclI site as an end point, no induction of nodC-lacZ or nodD-lacZ was observed. Therefore the promoters of nodD and nodA,B,C overlap at least at this region, and the regulation of these overlapping promoters appears to be controlled by the nodD protein which becomes an activator only in the presence of a component from plant exudate.

摘要

为了分析根瘤菌（Rhizobium leguminosarum）nod 基因的表达，构建了一个广谱宿主范围的 lacZ 蛋白融合载体。利用两个蛋白融合物 nodC-lacZ 和 nodD-lacZ，通过测量β-半乳糖苷酶活性的诱导水平，来测量 nodA、B、C 启动子和 nodD 转录物的表达调控。在没有植物根分泌物的情况下，nodD-lacZ 杂种被表达，但 nodC-lacZ 杂种没有被表达。在含有完整克隆 nodD 基因的根瘤菌菌株中，nodD-lacZ 杂种的表达受到抑制，表明 nodD 基因是自我调控的。nodC-lacZ 杂种的诱导需要 nodD 基因和植物根分泌物中的一个成分。因此，nodD 基因既作为抑制剂又作为激活剂来调节基因表达。nodD 基因与 nodA 相邻，并从 nodA、B、C 转录方向相反，在 nodA 和 nodD 的编码区之间只有大约 300 个核苷酸。在这个基因间区有一个独特的 BclI 位点，利用 nodC-lacZ 或 nodD-lacZ 与这个 BclI 位点的翻译融合作为终点，没有观察到 nodC-lacZ 或 nodD-lacZ 的诱导。因此，nodD 和 nodA、B、C 的启动子至少在这个区域重叠，并且这些重叠启动子的调节似乎受到 nodD 蛋白的控制，该蛋白只有在植物分泌物中的一个成分存在时才成为激活剂。