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Tetramethylthiuram disulfide or dimethyldithiocarbamate induces the synthesis of cadystins, heavy metal chelating peptides, in Schizosaccharomyces pombe.

作者信息

Mutoh N, Kawabata M, Hayashi Y

机构信息

Department of Genetics, Institute for Developmental Research, Aichi Prefectural Colony, Japan.

出版信息

Biochem Biophys Res Commun. 1991 May 15;176(3):1068-73. doi: 10.1016/0006-291x(91)90392-k.

DOI:10.1016/0006-291x(91)90392-k
PMID:1645536
Abstract

Tetramethylthiuram disulfide (TMTD) or dimethyldithiocarbamate (DMDTC) induces the synthesis of cadystins, a family of heavy metal chelating isopeptides with the formula (gamma-Glu-Cys)n-Gly (n = 2,3,4,...), in the fission yeast Schizosaccharomyces pombe. Amount of cadystins synthesized in TMTD or DMDTC treated cells is less than that synthesized in CdCl2 treated cells but much more than that synthesized in ZnCl2 or CuSO4 treated cells.

摘要

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